RECOMBINANT HUMAN GRANULOCYTE COLONY STIMULATING FACTOR

重组人粒细胞集落刺激因子

• 批准号: 5220182
• 负责人: KIMBERLY SMITH
• 金额: --
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/5220182
• 关键词: chemoprevention; clinical research; clinical trials; colony stimulating factor; drug screening /evaluation; glycogen storage disease type I; human subject; human therapy evaluation; leukocyte disorder; medical complication; metabolism disorder chemotherapy; neutrophil; recombinant proteins

The purpose of this study is to investigate the efficacy of r-metHuG-CSF to correct severe neutropenia secondary to glycogen storage disease (GSD) type 1b and to test the efficacy of G-CSF in correcting known neutrophil dysfunction in patients with GSD type 1b. The study will also evaluate the effects of daily G-CSF on the prevention/resolution of secondary outcome variables.

这项研究的目的是研究R-Methug-CSF的功效 纠正继发于糖原储存疾病（GSD）的严重中性粒细胞减少症 1B型并测试G-CSF在校正已知中性粒细胞的功效 GSD 1B型患者的功能障碍。 该研究还将评估 每日G-CSF对预防/解决次级的影响 结果变量。