IMPACT OF BIOLOGICAL CHANGES ON PSYCHOLOGICAL FUNCTIONING IN ADOLESCENCE

生物变化对青春期心理功能的影响

• 批准号: 3968513
• 负责人: E J SUSMAN
• 金额: --
• 依托单位: NATIONAL INSTITUTE OF MENTAL HEALTH
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3968513
• 关键词: adolescence (12-20); aggression; androgens; anxiety; behavior disorders; blood chemistry; body physical characteristic; child physical development; child psychology; child rearing; cognition; cortisol; depression; gender difference; hormone regulation /control mechanism; human puberty; human subject; interpersonal relations; longitudinal human study; middle childhood (6-11); mother child interaction; parent offspring interaction; personality tests; psychobiology; psychosexual development; self concept; sex hormones; social adjustment

Interrelations of adolescents' psychological functioning and endocrine and physical growth variables are investigated. Participants are 56 boys and 52 girls, 9 to 14 years old, and their parents. Participants were evaluated on biological and psychological variables at three times of measurement, six months apart. Biological measures include stage of pubertal development (Tanner stage), assessed by a physical examination, and hormone levels, assessed by serum levels of gonadotropins, gonadal steroids, adrenal androgens, and cortisol. Psychological measures include assessments of behavior problems, affective states, interpersonal functioning, parent-child interactions in standard laboratory situations, and cognitive functioning. Relations between hormone levels and anxiety and depressive symptoms, parent-child interactions, and cognitive functioning were examined. Hormone levels of boys, primarily gonadal steroids and adrenal androgens, were predictive of anxiety and depressive symptoms one year later. Hormone levels, per se, were not predictive of anxiety and depressive symptoms one year later in girls. A more rapid rate of change (across one year) in level of adrenal androgens in boys and gonadotropins in girls was accompanied by a higher incidence of anxiety and depressive symptoms at the year's end. Relations between hormone levels and the adolescent's use of anger and power in parent-adolescent interactions indicated that boys with higher levels of androstenedione were higher on explosive behavior. Girls with higher levels of androstenedione were higher on dominance, defiance, and expression of anger toward both mother and father. Relations between hormone levels and degree of peripheral target tissue exposure and cognitive functioning indicated that boys with higher testosterone levels and a greater degree of peripheral target tissue exposure were higher on spatial abilities than boys with less exposure to circulating gonadal steroids. Neither hormone levels nor degree of peripheral target tissue exposure was related to spatial abilities in girls.

青少年心理功能和内分泌的相互关系 研究身体生长变量。 参与者是56个男孩 52名9至14岁的女孩及其父母。 参与者是 对生物学和心理变量进行了三次评估 测量，相距六个月。 生物措施包括 通过体格检查评估的青春期发展（坦纳阶段） 和激素水平，通过促性腺激素的血清水平，促性腺肿 类固醇，肾上腺雄激素和皮质醇。 心理措施包括 评估行为问题，情感状态，人际关系 在标准实验室情况下的运作，亲子互动， 和认知功能。 激素水平与焦虑之间的关系 以及抑郁症状，亲子互动和认知 检查了功能。 男孩的激素水平，主要是性腺 类固醇和肾上腺雄激素可预测焦虑和抑郁 一年后的症状。 激素水平本身无法预测 一年后，女孩的焦虑和抑郁症状。 速度更快 男孩肾上腺雄激素水平的变化（一年） 女孩中的促性腺激素伴随着更高的焦虑发生率和 年底的抑郁症状。 激素水平之间的关系 以及青少年在父母青春期中使用愤怒和权力 相互作用表明雄性雌雄同体水平较高的男孩是 爆炸性行为更高。 雄激素含量较高的女孩 对两者的统治，反抗和愤怒的表达都更高 父亲和父亲。 激素水平与程度之间的关系 外围靶组织暴露和认知功能表明 睾丸激素水平较高且周围程度更高的男孩 与较少的男孩相比，空间能力的目标组织暴露更高 暴露于循环的性腺类固醇中。 激素水平既不 外围靶组织暴露程度与空间有关 女孩的能力。