MIXED CRYOGLOBULINEMIA--RETICULOENDOTHELIAL FUNCTION AND CHEMOTHERAPY

混合性冷球蛋白血症--网状内皮功能与化疗

• 批准号: 3904475
• 负责人: PETER GOREVIC
• 金额: --
• 依托单位: NEW YORK UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3904475
• 关键词: blood disorder chemotherapy; cryoglobulins; human subject; immune complex; plasmapheresis; renal failure; reticuloendothelial system

Patients will be studied before and after onset of renal dysfunction to better define if this defect is contributory to the pathogenesis of immune complex disposition or secondary to renal disease and to determine if chemotherapy and plasmapheresis may ameliorate the progressive and often fatal neurologic and renal manifestations of this disorder.

将在肾功能不全发生之前和之后对患者进行研究，以 更好地确定这种缺陷是否有助于发病机制 免疫复合物处置或继发于肾脏疾病并确定 化疗和血浆置换是否可以改善进行性和 这种疾病常常导致致命的神经系统和肾脏表现。