FATTY ALCOHOL METABOLISM IN SJOGREN-LARSSON SYNDROME

干燥-拉尔森综合征中的脂肪醇代谢

• 批准号: 3884149
• 负责人: WILLIAM R RIZZO
• 金额: --
• 依托单位: VIRGINIA COMMONWEALTH UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3884149
• 关键词: Sjogren's syndrome; alcohols; dietary control; dietary lipid; human subject; leukocytes; metabolism; plasma; skin; tissue /cell culture; urine

To document FAO deficiency in cultured skin fibroblasts and leukocytes. To establish the extent of fatty alcohol accumulation in the skin, plasma, leukocytes, erythrocytes, and urine. To investigate the biochemical and clinical response to dietary fat restriction.

记录FAO在培养的皮肤成纤维细胞和白细胞中的缺陷。 确定脂肪醇在皮肤、血浆、 白细胞、红细胞和尿液。 研究生化和 对膳食脂肪限制的临床反应。