MOLECULAR VIROLOGY AND IMMUNOLOGY LABORATORY

分子病毒学和免疫学实验室

• 批准号: 3725774
• 负责人: DORIS J LYONS
• 金额: $ 110万
• 依托单位: GEORGETOWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-10-16 至 1993-10-15
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3725774
• 关键词: AIDS; Hepadnaviridae; RNA directed DNA polymerase; enzyme linked immunosorbent assay; human immunodeficiency virus 1; monoclonal antibody; tissue /cell culture; virus protein; western blottings

The Division of Molecular Virology and Immunology, Georgetown University, supported the NIAID intramural and contract-sponsored extramural programs requiring the expertise and equipment of the NIAID special support laboratory at 5640 Fishers Lane, Rockville, Maryland under contract N01-AI-72623. Additional work was conducted outside the Rockville facility on-campus, at Georgetown, to support the NIAID intramural studies of the virology of the causative agent of AIDS (i.e., the isolation of virus from clinical specimens, purification and characterization of antigens, modification and development of assays for virus and antibodies to the virus). In addition to AIDS virus, the research efforts center on hepadna viruses, hepatitis delta virus; a hepatitis testing laboratory is provided; an electron microscope facility for collaborative studies on membrane receptors in neutrophil activation leading to chemotaxis and/or degranulation; and, mast cell aberrations in a variety of conditions associated with physiologic or pathologic mastocytoses. This contract (N01-AI-05058) was administratively split from N01-AI-72623 to support the work being done in support of DIR and AIDS research.

乔治敦分子病毒与免疫学的分工 大学支持NIAID壁内和合同赞助 需要NIAID的专业知识和设备的壁外计划 马里兰州罗克维尔市Fishers Lane 5640的特殊支持实验室 根据合同N01-AI-72623。 在外面进行了其他工作 乔治敦（Georgetown）校园里的洛克维尔（Rockville）设施，以支持Niaid 艾滋病病毒病毒学的壁内研究（即 从临床标本，纯化和 抗原的表征，修饰和开发测定 病毒和病毒的抗体）。 除了艾滋病病毒， 研究工作中心的肝炎病毒，乙型肝炎病毒；一个 提供了肝炎测试实验室；电子显微镜 关于中性粒细胞膜受体协作研究的设施 激活导致趋化性和/或脱粒；并且，肥大细胞 与生理学或 病理肥大症。 该合同（N01-AI-05058）是 从n01-ai-72623进行行政分配以支持正在完成的工作 支持DIR和AIDS研究。