LUMINOSA - LUminescent porphyrin Metal-organIc frameworks as oxygeN cOnsumption reporterS for bacteria-induced repair of concrete microcrAcks

LUMINOSA - 发光卟啉金属有机框架作为耗氧报告剂，用于细菌诱导的混凝土微裂纹修复

• 批准号: EP/Y015967/1
• 负责人: Leila Panahi
• 金额: $ 23.84万
• 依托单位: Liverpool John Moores University
• 依托单位国家: 英国
• 项目类别: Fellowship
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FY015967%2F1
• 关键词: LUMINOSA; LUminescent; porphyrin; Metal; organIc

Prompt intervention to repair cracks in concrete is crucial to prevent large-scale structural failures and avert consequent socioeconomic disruptions. Biomineralization recently emerged as an alternative to the current labour- and time-intensive concrete repair techniques, which cause a staggering 4-6 billion Eur yearly expenditure. Biomineralization exploits calcite precipitation promoted by bacteria seeded in concrete, sealing microcracks and preventing water penetration and fracture expansion. This approach can afford self-healing construction materials that drastically reduce the cost and carbon footprint of concrete structures maintenance. Development of biomineralization into a widely applied technique relies on the ability to monitor bacteria survival in concrete environment in real time, to guarantee reliable calcite deposition for optimal repair. The LUMINOSA project aims at developing innovative optical sensors to assess bacteria viability by mapping oxygen consumption in concrete microcracks during biomineralization treatment. We will synthesise a library of oxygen-responsive platinum porphyrins bearing carboxylic groups (Obj 1).We will incorporate these species in metal organic frameworks (MOFs) to afford luminescent sensors with enhanced response in aqueous environment (Obj 2). We will exploit the oxygen responsiveness of the MOFs to visualise/map oxygen consumption by biomineralization-capable bacteria populations in concrete microcracks (Obj 3). Successful delivery of this project will widen the applicability of optical sensing in biomineralization, deepening field-specific knowledge and enabling a high-impacting technology for societal benefit. This highly interdisciplinary project is tailored to enhance the prospect of academic career through building a broad research portfolio, generating opportunities to forge independent intersectoral networks, strengthening track record and expanding research specific and transferrable skills.

及时干预修复混凝土裂缝对于防止大规模结构失效并避免随之而来的社会经济破坏至关重要。最近出现的生物矿化作为目前劳动密集型和时间密集型混凝土修复技术的替代技术，这种技术每年造成 4-60 亿欧元的支出。生物矿化利用混凝土中接种的细菌促进方解石沉淀，密封微裂纹并防止水渗透和裂缝扩展。这种方法可以提供自我修复的建筑材料，从而大大降低混凝土结构维护的成本和碳足迹。生物矿化发展成为广泛应用的技术依赖于实时监测混凝土环境中细菌存活的能力，以保证可靠的方解石沉积以实现最佳修复。 LUMINOSA 项目旨在开发创新的光学传感器，通过绘制生物矿化处理过程中混凝土微裂纹中的耗氧量来评估细菌的活力。我们将合成一个带有羧基的氧响应性铂卟啉库（目标 1）。我们将这些物质合并到金属有机框架（MOF）中，以提供在水环境中具有增强响应的发光传感器（目标 2）。我们将利用 MOF 的氧响应性来可视化/绘制混凝土微裂缝中具有生物矿化能力的细菌群的耗氧量（对象 3）。该项目的成功交付将扩大光学传感在生物矿化中的适用性，加深特定领域的知识，并实现具有社会效益的高影响力技术。这个高度跨学科的项目旨在通过建立广泛的研究组合、创造建立独立的跨部门网络的机会、加强跟踪记录并扩大研究特定和可转移技能来增强学术职业前景。