CORE--INFORMATICS

核心--信息学

• 批准号: 3779433
• 负责人: N W MATHESON
• 金额: --
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3779433
• 关键词: biomedical resource; computer assisted sequence analysis; computer human interaction; computer program /software; cooperative study; data collection; genetic mapping; human genetic material tag; information systems; nucleic acid sequence

The overall goal of the Informatics Core is to develop, maintain, and make available a consensus gene mapping and disease database which supports the scientific community in the mapping and sequencing of the entire human genome and which will serve as a resource for biological and medical applications. The specific aims of this project can be broken down into 3 major areas: 1. Products Development . To design and build a dynamic database which integrates comprehensive gene mapping and disease data with linkages to other related databases which support the human genome initiative. . To develop editorial and administrative tools for collecting scientific data and maintaining its currency, integrity and quality. . To monitor the latest advances and tools in database technology and software engineering and to integrate into the production system when appropriate. 2. Product Services To make all genomic data collected by the database freely and easily available to the international scientific community through multiple database and software products. To design and deliver high quality services related to the use and distribution of the database. To develop and conduct a community training and information program for enhanced knowledge and use of the database.  To maintain and make available complete software, system, and user documentation. 3. Infrastructure Support To implement and maintain a robust computing and communications infrastructure sufficient to support Product Development and Product Services and to meet the demands of international database editing and access.  To ensure data and system reliability, security, and integrity. This work will be accomplished by the Laboratory for Applied Research in Academic Information.

信息学核心的总体目标是开发、维护和制作 可获得共识基因图谱和疾病数据库，支持 科学界对整个人类进行绘图和测序 基因组，将作为生物和医学的资源 应用程序。 该项目的具体目标可分为3个 主要领域： 1. 产品开发 。设计并建立一个综合性的动态数据库 基因图谱和疾病数据与其他相关数据库的链接 支持人类基因组倡议。 。开发收集科学数据的编辑和管理工具 数据并保持其流通性、完整性和质量。 。监控数据库技术的最新进展和工具 软件工程并集成到生产系统中 合适的。 2、产品服务 让数据库采集的所有基因组数据变得自由、便捷 通过多种方式向国际科学界提供 数据库和软件产品。 设计和提供与使用和相关的高质量服务 数据库的分布。 制定并开展社区培训和信息计划 增强对数据库的认识和使用。 维护并提供完整的软件、系统和用户 文档。 3. 基础设施支持 实施和维护强大的计算和通信 足以支持产品开发和产品的基础设施 服务并满足国际数据库编辑和需求 使用权。 确保数据和系统的可靠性、安全性和完整性。 这项工作将由应用研究实验室完成 学术信息。