COOPERATIVE HUMAN TISSUE NETWORK--PEDIATRIC DIVISION

人体组织合作网络--儿科

• 批准号: 2095629
• 负责人: STEPHEN J QUALMAN
• 金额: $ 24.47万
• 依托单位: CHILDREN'S HOSPITAL (COLUMBUS)
• 依托单位国家: 美国
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-01-01 至 1995-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2095629
• 关键词: cancer registry /resource; child (0-11); cooperative study; human tissue; pediatric neoplasm /cancer; tissue resource /registry

The need and feasibility of a national center for the procuring, banking, and distribution of pediatric specimens for use in biologic research has been demonstrated. The broad, long-term objectives of this application are: 1) continue the role of the Childrens Cancer Study Group (CCSG) as the main source, provider, and distributor of pediatric specimens as the Cooperative Human Tissue Network Pediatric Division; 2) expand the availability of these tissues to biologic cancer researchers nationally; 3) stimulate cancer research through this increase of access to scientifically valuable material; 4) create a long-term repository for pediatric tumors to make large numbers of tumors available for scientific breakthroughs that require a critical number of specimens at one time. The CCSG Pathology Center, located at Children's Hospital of Columbus, Ohio and serving as the Network's Pediatric Division, will continue to direct the flow of specimens and information from participating CCSG institutions to researchers nationally. The procurement of tissue and distribution to investigators (both directly and indirectly), and where appropriate, banking of rare pediatric tumors, will provide both CCSG and non-CCSG investigators with a broad-based and organized source of specimens for biologic research. The Pediatric Division, under the governance of and through participation in the CHTN Coordinating Committee, will strive to fulfill the individual needs of each investigator while maintaining its established standards of quality, confidentiality, and cost-effectiveness. The ultimate goal of this application is to make the most out of a severely limited resource.

国家采购，银行业中心的需求和可行性 和用于生物学研究的小儿标本的分布 被证明了。本应用程序的广泛，长期目标是： 1）继续儿童癌研究组（CCSG）作为主要的作用 儿科标本的资料来源，提供商和分销商作为合作 人体组织网络小儿分层； 2）扩大可用性 这些组织到全国生物癌研究人员； 3）刺激 癌症研究通过增加科学有价值的机会 材料; 4）创建一个长期存储库，以使小儿肿瘤制作 可用于科学突破的大量肿瘤需要 一次关键标本。 CCSG病理中心，位于俄亥俄州哥伦布儿童医院 并担任网络的儿科部门，将继续指导 参与CCSG机构的标本和信息的流动 给全国研究人员。组织的采购和分布到 调查人员（直接和间接），并且在适当的情况下， 罕见的小儿肿瘤的储备将同时提供CCSG和非CCSG 具有广泛和有组织的标本来源的调查员 生物学研究。 小儿分区，在参与的治理下 在CHTN协调委员会中，将努力实现个人 每个调查员的需求，同时保持其既定标准 质量，机密性和成本效益。最终目标 应用是为了充分利用严重有限的资源。