QUALITY ASSURANCE REVIEW CENTER (QARC)

质量保证审查中心 (QARC)

• 批准号: 2087938
• 负责人: ARVIN S. GLICKSMAN
• 金额: $ 49.02万
• 依托单位: ROGER WILLIAMS HOSPITAL
• 依托单位国家: 美国
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-08-15 至 1995-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2087938
• 关键词: Ewing's tumor; Hodgkin's disease; acute leukemia; brain neoplasms; cancer information system; cooperative study; genetic manipulation; health care service evaluation; human subject; human therapy evaluation; imaging /visualization /scanning; information retrieval; lung neoplasms; mathematical model; neoplasm /cancer radiation therapy; neoplasm /cancer radiodiagnosis; nephroblastoma; pediatric neoplasm /cancer; radiation therapy dosage; rhabdomyosarcoma; workshop

The primary goal of the Quality Assurance Review Center is to maintain a responsive, supportive Quality Assurance Program in Radiotherapy for Cooperative Groups. We wish to continue development and implementation of the Program, since it has proven effective in improving the performance of the many gains accomplished in the past decade, leading to improvements in Group performance and with an elevation in sophistication of the Radio-therapy and Physics community in supporting clinical trials, our program, in the future, should take advantage of the improvements without losing ground in the process. In this grant cycle, we propose to undertake a modernization of our Data Management system. We will improve methods of data transfer to Group Investigators and Statistical Offices, with a wide rang of formats. We further propose to reorient Physics support for Group trials by modifying their participation in the development of protocols, in the way Physics data is accumulated and develop a novel approach to the study of radiation effects. The QARC has acted as a research resource for the Cooperative Groups; we are proposing to establish this as a recognized function at QARC. This includes developing normal tissue protocol questions. Secondly, because of the robust data-base that we have developed, we can work with Group Investigators and Statistical Offices to make available subsets of our data for correlative analyses of the radiotherapy performance as it relates to outcome. Because of QARC's recognized ability for Data Management, we have accepted responsibility for accumulation of Diagnostic Imaging data not necessarily a component of the section on Data Management for Diagnostic Imaging materials to support Group trials. Since its initiation a decade ago, QARC has responded to a demonstrated need of the Radiotherapy community in Cooperative Group trials and we propose to continue to be responsive to the changing needs during the period of this grant proposal.

质量保证审查中心的主要目标是维护 放射疗法的响应迅速，支持性的质量保证计划 合作团体。我们希望继续开发和实施 该计划的事实证明有效地改善了 在过去十年中取得的许多收益的表现，领先 提高小组绩效并提高 放射治疗和物理社区的复杂性支持 临床试验，我们的计划将来应该利用 在此过程中没有失去立场的改进。 在这个赠款周期中， 我们建议对数据管理系统进行现代化。 我们将改善数据传输方式到小组调查人员以及 统计局，具有广泛的格式。 我们进一步建议 通过修改他们的小组试验的重新定向物理支持 以物理数据的方式参与协议的开发 积累并开发了一种新的方法来研究辐射 效果。 QARC充当合作社的研究资源 群体；我们建议将其确定为公认的功能 qarc。 这包括制定正常组织方案问题。 其次，由于我们开发了强大的数据库，我们可以 与小组调查员和统计办公室合作以提供 我们的数据子集用于放射疗法的相关分析 与结果有关的表现。 由于QARC的认可 数据管理能力，我们接受了 诊断成像数据的积累不一定是 有关诊断成像材料数据管理的部分 支持小组试验。 自十年前的启动以来，Qarc拥有 回应了对放射治疗社区的需求 合作小组试验，我们建议继续对 在此赠款提案期间的需求不断变化。