TEACHING NURSING HOME

教学疗养院

• 批准号: 3090755
• 负责人: HOWARD A CRYSTAL
• 金额: $ 76.17万
• 依托单位: ALBERT EINSTEIN COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 1982
• 资助国家: 美国
• 起止时间: 1982-09-29 至 1992-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3090755
• 关键词: aging; human old age (65+); human subject

This proposal requests support to continue the Teaching Nursing Home, a multi-site, multi-institutional program project. This TNH represents a reorganization of resources relating to geriatric research into a structure which crosses institutional, departmental and disciplinary lines. Participating organizations include: the Albert Einstein College of Medicine, Montefiore Medical Center, and their four associated long term care facilities, and the College of Mt. St. Vincent Nursing Program. Five research protocols are organized around a strong service core, which includes a common subject pool, shared assessment personnel, shared assessments, a shared database, shared data management and analysis, and shared neuropathologic correlation. The five component research projects study: dementia, osteoarthritis, motor-control impairment, age-associated memory impairment, and congestive heart failure, and include clinical and laboratory investigations. By the end of the next five years, we should have developed a comprehensive database on more than 1000 research subjects and: 1) determined which factors in history, neurologic exam, neuropsychological profile, neuro-imaging, or biochemical markers improve diagnostic accuracy in Alzheimer's disease (AD), and evaluated pathological criteria which differentiate AD from normal aging; 2) described gait and balance in normal elderly; described the natural history of fallers; identified predictors of falling; and defined pathophysiologic mechanisms of motor control and implications for intervention; 3) identified biological markers in synovial fluid and described Osteoarthritis in a spectrum of persons with joint complaints; 4) delineated the syndrome of Age- Associated Memory Impairment and its course, and 5) clarified the syndrome of congestive heart failure in a cohort of old . In short, we will have conducted research on conditions which severely affect the quality of life of older persons, and this project will, hopefully, have an important impact on geriatric practice and care.

该提案请求支持继续进行护理教学 Home，一个多地点、多机构的计划项目。 这 TNH 代表与老年病相关的资源重组 研究跨机构的结构， 部门和纪律界限。 参与机构 包括：阿尔伯特·爱因斯坦医学院，蒙蒂菲奥里 医疗中心及其四个相关的长期护理 设施和圣文森特山学院护理项目。 围绕强大的服务组织了五个研究方案 核心，包括共同主题库、共享评估 人员、共享评估、共享数据库、共享数据 管理和分析，以及共享的神经病理学相关性。 五个组成部分的研究项目研究：痴呆症、 骨关节炎、运动控制障碍、年龄相关记忆 损伤和充血性心力衰竭，包括临床和 实验室调查。 到未来五年结束时，我们应该开发出 包含 1000 多个研究主题的综合数据库，以及： 1）确定病史、神经系统检查中的哪些因素， 神经心理学概况、神经影像学或生化 标记物提高了阿尔茨海默病（AD）的诊断准确性， 并评估了区分 AD 和 AD 的病理标准 正常老化； 2）描述正常老年人的步态和平衡； 描述了跌倒者的自然历史；确定的预测因素 坠落；并明确了运动控制的病理生理机制 以及对干预的影响； 3) 鉴定的生物标记 滑液中并描述了一系列骨关节炎 有共同投诉的人； 4）描述了年龄综合症- 相关记忆障碍及其过程，以及 5) 澄清 老年人充血性心力衰竭综合症。 在 简而言之，我们将对以下条件进行研究： 严重影响老年人的生活质量， 希望该项目将对老年医学产生重要影响 练习和护理。