CORONARY HEART DISEASE AND STROKE IN PEOPLE AGED 65-84

65-84 岁人群的冠心病和中风

• 批准号: 3647842
• 负责人: DANIEL O'LEARY
• 金额: $ 21.09万
• 依托单位: NEW ENGLAND DEACONESS HOSPITAL
• 依托单位国家: 美国
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-06-28 至 1994-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3647842
• 关键词: aging; atherosclerosis; cardiovascular disorder epidemiology; coronary disorder; diet; disease /disorder proneness /risk; health care service utilization; human old age (65+); human subject; nutrition related tag; physical fitness; physiologic stressor; social support network; stroke

The primary purpose of this project is to investigate risk factors for coronary heart disease (CHD) and stroke in the elderly. Risk factors for the development and progression of cardiovascular diseases will be examined in an elderly cohort. Risk factors for development of overt cardiovascular disease in an older population with prevalent atherosclerosis may differ from those related to the development of atherosclerosis in a younger population. In an elderly population with prevalent atherosclerosis it is important to assess the prediction of clinical disease from measures of preclinical disease such as carotid atherosclerosis. The primary objective of the Ultrasound Reading Center is to develop and implement a system to assess atherosclerosis in the carotid arteries using ultrasound. This will involve 1) coordinating development of a protocol for ultrasound examinations at the Field Centers and a method for evaluating extent of carotid atherosclerosis, 2) training ultrasound technicians of each Field Center, 3) interpreting all ultrasound examinations and 4) monitoring the ultrasound examinations at all Field Centers. During the periods of data collection, the Ultrasound Reading Center shall have the responsibility of assessing within and between individual variation among technicians and coders. The contractor shall serve as the Ultrasound Reading Center for this study. Duties of the Ultrasound Reading Center include equipment selection, protocol development, technician training, central reading' and data transmittal and analysis for the ultrasonographic examinations within the elderly study.

该项目的主要目的是调查风险因素 用于老年人冠心病（CHD）和中风。 风险 心血管疾病发生和进展的因素 疾病将在老年人群中进行检查。 危险因素 老年人群中明显心血管疾病的发展 与普遍的动脉粥样硬化有关的疾病可能与那些相关的疾病不同 年轻人群中动脉粥样硬化的发展。 在患有普遍动脉粥样硬化的老年人群中， 对于评估临床疾病的预测很重要 颈动脉粥样硬化等临床前疾病的测量。 超声解读中心的主要目标是 开发并实施评估动脉粥样硬化的系统 使用超声波检查颈动脉。 这将涉及 1) 协调超声检查方案的制定 现场中心和评估颈动脉范围的方法 动脉粥样硬化，2）培训各领域超声技术人员 中心，3) 解释所有超声检查以及 4) 监测所有现场中心的超声检查。 在数据收集期间，超声读数 中心有责任在内部和外部进行评估 技术人员和编码员之间的个体差异。 承包商应作为超声读数中心 这项研究。 超声解读中心的职责包括 设备选择、方案制定、技术人员培训、 集中读取和数据传输和分析 老年人研究中的超声检查。