EPR NRF Core Equipment Bid

EPR NRF核心设备招标

基本信息

  • 批准号:
    EP/V035231/1
  • 负责人:
  • 金额:
    $ 56.64万
  • 依托单位:
  • 依托单位国家:
    英国
  • 项目类别:
    Research Grant
  • 财政年份:
    2020
  • 资助国家:
    英国
  • 起止时间:
    2020 至 无数据
  • 项目状态:
    已结题

项目摘要

Electron Paramagnetic Resonance (EPR) spectroscopy, also known as Electron Spin Resonance (ESR), is possibly the most powerful technique for characterisation of paramagnetic materials, i.e. that contain unpaired electrons. Unpaired electrons give rise to the magnetic and electronic properties of materials and often govern reactivity when present, hence understanding their environment and behaviour is important. Paramagnets are ubiquitous from biological processes to magnetic materials; hence EPR is an essential tool in physics, chemistry, materials and biological sciences.The EPSRC funds a National Research Facility (NRF) for EPR, located in the Photon Science Institute (PSI) at The University of Manchester (UoM), providing access to state-of-the art experimental techniques and expertise for the UK academic community. Crudely, there are two ways to do EPR spectroscopy: continuous wave (cw) EPR and pulsed EPR, which give complementary information. Pulsed EPR is a much higher resolution technique (allowing measurement of much weaker interactions involving the unpaired electron) and also gives access to time-resolved information. However, such experiments are often very slow, requiring long data collection to get acceptable signal-to-noise (e.g. due to low paramagnet concentration) and/or a wide range of experimental conditions (e.g. different applied magnetic fields, or timings of the experiment). It is common for an experiment on a single sample to last a week of continuous measurement. As a consequence, the two pulsed EPR spectrometers that the EPR NRF currently runs are by far and away the most over-subscribed pieces of instrumentation.There is currently a second EPR facility at the UoM, based in the Manchester Institute of Biotechnology (MIB), which houses a pulsed spectrometer that was commissioned in 2009. Here we are proposing to expand the capacity and capability of the EPR NRF by upgrading the MIB spectrometer and relocating and incorporating it into the NRF in the PSI. This upgrade and relocation will enhance the capacity for pulsed EPR in the NRF by 50% at minimal cost. Almost all pulsed EPR needs to be performed at low temperatures, requiring liquid helium cooling. Helium is an expensive and finite resource. The second part of the proposal is to install a closed-system cryogen-free cryostat to the upgraded instrument, allowing continuous measurement down to a base temperature of <2 K. This is lower than we can currently reach at X-band, which will enable study of a wider range of materials. It will also almost entirely remove the need for liquid helium in the NRF. The new complete spectrometer system will increase the capacity for pulsed EPR for all users of the NRF across the UK, including ECRs and doctoral students, and the new capability will widen the user base. Finally, the new kit will enable us to expand our regular training workshops because attendee numbers are limited by spectrometer access.To contact the National EPR Facility and Service, please email: epr@manchester.ac.uk
电子顺磁共振(EPR)光谱,也称为电子自旋共振(ESR),可能是表征顺磁性材料的最强大技术,即包含不成对电子的电子。未配对的电子产生材料的磁性和电子特性,并且在存在时通常会控制反应性,因此了解其环境和行为很重要。从生物过程到磁性材料,Paramagnets无处不在。因此,EPR是物理,化学,材料和生物科学的重要工具。粗略地,进行EPR光谱的方法有两种方法:连续波(CW)EPR和脉冲EPR,提供互补信息。脉冲EPR是一种更高的分辨率技术(允许测量涉及未配对电子的弱相互作用),并且还可以访问时间分辨信息。但是,这样的实验通常非常慢,需要长的数据收集才能获得可接受的信噪比(例如,由于较低的Paramagnet浓度)和/或广泛的实验条件(例如,不同的磁场或实验的时机)。在单个样本上进行实验通常是连续测量的一周。结果,EPR NRF当前运行的两个脉冲EPR光谱仪是迄今为止最过多的仪器。目前在UOM的第二个EPR设施,位于曼彻斯特生物技术学院(MIB)(MIB)的UOM中,该设施在2009年均扩展了ERF的underformitive。升级MIB光谱仪并将其重新定位到PSI中的NRF中。此升级和搬迁将以最低的成本提高NRF中脉冲EPR的能力50%。几乎所有脉冲EPR都需要在低温下进行,需要液态氦气冷却。氦是一种昂贵且有限的资源。该提案的第二部分是在升级的仪器上安装一个无雪茄的低温恒温器,从而可以连续测量至<2 k的基础温度。这比我们目前可以达到的X频段低,这将促进更多材料范围的研究。它也几乎完全消除了NRF中液态氦气的需求。新的完整光谱仪系统将增加英国所有NRF的所有用户(包括ECRS和博士生)的脉冲EPR的能力,而新功能将扩大用户群。最后,新套件将使我们能够扩大常规培训研讨会,因为与会者的电话会受到光谱仪的访问限制。要联系国家EPR设施和服务,请发送电子邮件至epr@manchester.ac.uk

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

David Collison其他文献

Constructing meaning in the service of power: An analysis of the typical modes of ideology in accounting textbooks
  • DOI:
    10.1016/j.cpa.2009.02.002
  • 发表时间:
    2009-11-01
  • 期刊:
  • 影响因子:
  • 作者:
    John Ferguson;David Collison;David Power;Lorna Stevenson
  • 通讯作者:
    Lorna Stevenson
Manganese (III) fluoride as a new synthon in Mn cluster chemistry
  • DOI:
    10.1016/j.poly.2005.03.045
  • 发表时间:
    2005-11-17
  • 期刊:
  • 影响因子:
  • 作者:
    Leigh F. Jones;Jim Raftery;Simon J. Teat;David Collison;Euan K. Brechin
  • 通讯作者:
    Euan K. Brechin
The Development of Macro Environmental Accounting
宏观环境核算的发展
マクロ環境会計の展開
宏观环境核算的发展
  • DOI:
  • 发表时间:
    2002
  • 期刊:
  • 影响因子:
    0
  • 作者:
    David Collison;Yosinao Kozuma;小口好昭
  • 通讯作者:
    小口好昭
After Enron is "Japan Inc" a better business model? (Part1・Part2)
安然之后“日本公司”是更好的商业模式吗?(第一部分・第二部分)

David Collison的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

{{ truncateString('David Collison', 18)}}的其他基金

Capital Award for Core Equipment 2022/23, National Research Facility for Electron Paramagnetic Resonance Spectroscopy
2022/23年度核心设备资本奖,国家电子顺磁共振波谱研究装置
  • 批准号:
    EP/X034623/1
  • 财政年份:
    2023
  • 资助金额:
    $ 56.64万
  • 项目类别:
    Research Grant
A National Research Facility for EPR Spectroscopy, 2022-2027
国家 EPR 光谱研究设施,2022-2027
  • 批准号:
    EP/W014521/1
  • 财政年份:
    2022
  • 资助金额:
    $ 56.64万
  • 项目类别:
    Research Grant
A National Service for Electron Paramagnetic Resonance, 2006-2011
国家电子顺磁共振服务,2006-2011
  • 批准号:
    EP/D050782/1
  • 财政年份:
    2006
  • 资助金额:
    $ 56.64万
  • 项目类别:
    Research Grant

相似国自然基金

基于NRF2调控KPNB1促进PD-L1核转位介导非小细胞肺癌免疫治疗耐药的机制研究
  • 批准号:
    82303969
  • 批准年份:
    2023
  • 资助金额:
    30 万元
  • 项目类别:
    青年科学基金项目
TFEB介导自噬调控Nrf2核转位在间歇性低氧认知损害中的作用及机制
  • 批准号:
    82301672
  • 批准年份:
    2023
  • 资助金额:
    30 万元
  • 项目类别:
    青年科学基金项目
磷酸烯醇丙酮酸修饰KEAP1减少NRF2核转位并抑制肝癌增殖的机制研究
  • 批准号:
    82303236
  • 批准年份:
    2023
  • 资助金额:
    30 万元
  • 项目类别:
    青年科学基金项目
干细胞外泌体调控Nrf2的m6A甲基化抑制退变髓核细胞溶酶体膜透化的机制研究
  • 批准号:
    82372477
  • 批准年份:
    2023
  • 资助金额:
    74 万元
  • 项目类别:
    面上项目

相似海外基金

Establishment of Isotope 3D imaging by LCS-NRF Method
LCS-NRF同位素3D成像方法的建立
  • 批准号:
    18H01916
  • 财政年份:
    2018
  • 资助金额:
    $ 56.64万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
新規ターゲット因子に着目した化学物質の神経毒性評価系構築と生体リスク評価
聚焦新目标因子的化学物质神经毒性评价体系构建及生物风险评估
  • 批准号:
    18J01790
  • 财政年份:
    2018
  • 资助金额:
    $ 56.64万
  • 项目类别:
    Grant-in-Aid for JSPS Fellows
Neurotoxicity of organotins via nuclear respiratory factor-1 (NRF-1) inhibition
有机锡通过抑制核呼吸因子 1 (NRF-1) 产生的神经毒性
  • 批准号:
    15H02826
  • 财政年份:
    2015
  • 资助金额:
    $ 56.64万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Study on 3D-CT Isotope Imaging by NRF
NRF 3D-CT同位素成像研究
  • 批准号:
    26289363
  • 财政年份:
    2014
  • 资助金额:
    $ 56.64万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Study on Isotope Imaging by using Nuclear Resonance Fluorescence induced by Laser Compton Scattering Gamma-ray Beam
激光康普顿散射伽马射线束诱导核共振荧光同位素成像研究
  • 批准号:
    21360467
  • 财政年份:
    2009
  • 资助金额:
    $ 56.64万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了