CLINICAL ASPECTS OF DE/REMINERALIZATION OF TEETH

牙齿脱矿/再矿化的临床表现

• 批准号: 2131223
• 负责人: JOHN D FEATHERSTONE
• 金额: $ 0.5万
• 依托单位: EASTMAN DENTAL CENTER
• 依托单位国家: 美国
• 财政年份: 1993
• 资助国家: 美国
• 起止时间: 1993-04-01 至 1995-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2131223
• 关键词: dental research; meeting /conference /symposium; tooth; travel

The purpose of this proposal is to hold an International Scientific Meeting (conference/workshop) on the topic: The translation of tooth demineralization/remineralization research findings and technology from the laboratory to clinical application in the human mouth. The short title will be "Conference on clinical aspects of de/remineralization of teeth". The objective of the conference/workshop is to bring together expert researchers in the area of tooth de- and remineralization (both laboratory, i.e. in vitro and animal, and human in vivo areas) to facilitate discussions and interchange of information that will transfer existing and future knowledge into more effective means of prevention of dental caries. The specific aims of the conference/workshop are: 1. To assess the current status of research in the area of tooth demineralization/remineralization as it relates to caries prevention (both coronal and root surface), and in particular, to assess whether de/remin models are actually representative of clinical reality. 2. To assess the validity and reliability of (a) in vitro models, (b) animal models, and (c) human in situ models as mechanisms for understanding and predicting outcomes of clinical caries studies. One of the ultimate goals will be the substitution, where possible, of valid and reliable models for more lengthy and costly clinical trials. 3. To assess the usefulness of these models to assist in identifying patients at risk (of dental caries). 4. To develop a new research agenda for clinical studies of demineralization and remineralization. 5. To recommend new and future research initiatives and prioritize these to improve caries preventive methods. The conference will be held in June, 1994 at the Woodcliff Conference Center, Rochester, NY immediately following the IADR meeting in Chicago. Approximately 50 invited participants and 50-100 self-pay observers will meet in plenary sessions and individual workshop groups to produce a consensus to fulfill the above specific aims and objectives. The conference proceedings will be published (most likely in Advances in Dental Research).

该提议的目的是持有国际科学 会议（会议/研讨会）有关该主题的：牙齿的翻译 脱矿业/回忆研究结果和技术 人口临床应用实验室。 短 标题将是“关于DE/RESERESERIZAIDS临床方面的会议 牙齿”。 会议/研讨会的目的是将专家汇集在一起 牙齿去矿化领域的研究人员（都 实验室，即体外和动物，在体内地区） 促进将转移的信息讨论和互换 现有的和未来的知识，以更有效的预防手段 龋齿。 会议/研讨会的具体目的是： 1。评估牙齿区域研究的当前状态 与龋齿预防有关 （冠状和根表面），特别是评估是否 DE/REMIN模型实际上是临床现实的代表。 2。评估（a）体外模型的有效性和可靠性，（b） 动物模型和（c）人类原位模型作为机制 理解和预测临床龋齿研究的结果。 之一 最终目标将在可能的情况下取代有效，并且 可靠的模型，用于更长时间和昂贵的临床试验。 3。评估这些模型的有用性以帮助识别 有风险的患者（龋齿）。 4。为临床研究制定新的研究议程 矿化和回忆。 5。推荐新的和未来的研究计划，并将其优先考虑 改善龋齿预防方法。 会议将于1994年6月在伍德克利夫会议上举行 在芝加哥举行的IADR会议之后，纽约州罗切斯特市中心。 大约有50名受邀参与者和50-100个自付的观察者将 在全体会议和单个研讨会小组中开会，以产生 达成满足上述特定目标和目标的共识。 这 会议诉讼将发布（最有可能在 牙科研究）。