1985 GORDON CONFERENCE ON OXYGEN RADICALS

1985 年戈登氧自由基会议

基本信息

批准号：
3433818
负责人：
WILLIAM A PRYOR
金额：
$ 1.2万
依托单位：
GORDON RESEARCH CONFERENCES
依托单位国家：
美国
项目类别：
财政年份：
1985
资助国家：
美国
起止时间：
1985-02-01 至 1986-01-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/3433818
关键词：
hydrogen peroxide hydroxyl group superoxides travel

项目摘要

A Gordon Research Conference on "Oxygen Radicals in Biology and Medicine" has been arranged for 10-15 February, 1985 at the Miramar Hotel in Santa Barbara, CA. It is the purpose of this conference to bring together chemists, biochemists, cell biologists, and clinicians who deal with the issue of oxygen radicals in their research programs. Funds are requested to help support travel and 5 days of housing and subsistence for 20 speakers and 9 session chairmen. Selection of speakers has been completed with the participation of a nine member advisory board. The list of speakers includes many major investigators whose contributions are certain to be novel and stimulating. Participation will be limited to about 20-50 people. The program will be composed of 5 morning, and 3 evening sessions of 2-3 hours each, and one keynote talk following an evening banquet. Posters will be presented during the intervening hours. Topics covered with slide presentations are: chemistry of oxygen radicals, biochemistry of oxygen radicals, clinical aspects, toxin-mediated reactions - P450 etc., enzymes, drugs, quinones and related subjects, cell targets (PG's, co-oxidations, etc.), and cancer and aging. The Conference provides its participants with an unmatched environment for total immersion during one work-week of at least 12 hours daily of meetings, discussion, and individual contacts. It is particularly timely, as the interest in oxygen radicals has increased greatly amongst clinicians who are becoming more aware of the potential production of these species in humans and of their potential pathological consequences. For example, oxygen-radical damage has been implicated in inflammation arthritis, adult respiratory-distress syndrome, myocardial infarction, pulmonary dysfunction in hemodialized patients, Purtscher's syndrome, Bloom's syndrome, Systemic Lupis Erythematosis, mutagenicity, and carcinogenicity. This list is not exhaustive, nor does it reflect that adequate experimental data has been presented to support the involvement of oxygen radicals in these conditions. The Conference is designed to stimulate new ideas, heighten awareness of recent discoveries in basic research and focus on human health implications.

戈登（Gordon）关于“生物学和医学氧基” 已于1985年2月10日至15日在圣诞老人的Miramar Hotel安排加利福尼亚州芭芭拉这是这次会议的目的化学家，生物化学家，细胞生物学家和临床医生其研究计划中的氧激活者问题。要求资金帮助支持旅行以及5天的住房和维持生计20 演讲者和9届会议主席。演讲者的选择已完成随着九个成员顾问委员会的参与。列表演讲者包括许多主要调查人员，他们的贡献可以确定是新颖和刺激的。参与将仅限于20-50 人们。该计划将由第五天早上和3个晚上的会议组成每个宴会之后，每个2-3个小时，以及一个主题演讲。海报将在此期间出现。涵盖了主题幻灯片演示是：氧自由基的化学，生物化学氧自由基，临床方面，毒素介导的反应-P450等，酶，药物，奎因酮和相关受试者，细胞靶标（PG，共氧化等）以及癌症和衰老。该会议为参与者提供了无与伦比的环境每天至少12个小时的工作中的总浸入会议，讨论和个人联系。特别及时随着对氧自由基的兴趣在临床医生中大大增加谁越来越了解这些物种的潜在产生人类及其潜在的病理后果。例如，氧基激进损害与炎症关节炎有关呼吸道综合综合症，心肌梗塞，肺功能障碍在血液序列化的患者中卢皮斯红斑病，诱变性和致癌性。此列表不是详尽的，也没有反映出足够的实验数据提出以支持氧自由基参与其中状况。会议旨在刺激新想法，增强意识到基础研究中最新发现并关注人类健康含义。