OLFACTORY AND NEUROENDOCRINE FUNCTIONS

嗅觉和神经内分泌功能

• 批准号: 3394821
• 负责人: FOTEOS MACRIDES
• 金额: $ 29.09万
• 依托单位: WORCESTER FOUNDATION FOR BIOMEDICAL RES
• 依托单位国家: 美国
• 财政年份: 1978
• 资助国家: 美国
• 起止时间: 1978-07-01 至 1988-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3394821
• 关键词: automated data processing; electrophysiology; hormone regulation /control mechanism; limbic system; neural information processing; neural transmission; neuroanatomy; neuroendocrine system; nontherapeutic iontophoresis; olfactions; olfactory stimulus; pheromone; pituitary gonadal axis; psychophysiology; sex behavior; social behavior

We are conducting a coordinated program of neurophysiological, neuroanatomical, endocrinological and biochemical research on the sensory and hormonal basis of olfactory discrimination in mammals. The objectives of the research include (1) chemical identification of biologically active constituents in pheromonal secretions, (2) study of the mechanisms by which these substances affect neuroendocrine and reproductive functions, (3) characterization of the mechanisms by which changes in hormonal secretion influence the neural processing of biologically relevant stimuli, (4) specification of the anatomical and neurochemical relationships among structures of the olfactory and limbic-hypothalamic systems, and (5) examination of the functional significance of reciprocal connections among these forebrain structures.

我们正在进行一个协调的神经生理学计划， 关于感觉的神经解剖学，内分泌学和生化研究 哺乳动物中嗅觉歧视的荷尔蒙基础。 目标 研究包括（1）化学鉴定生物活性 信息符号分泌的成分，（2）研究的机制 这些物质会影响神经内分泌和生殖功能，（3） 激素分泌变化的机制的表征 影响生物学相关刺激的神经加工，（4） 解剖学和神经化学关系的规范 嗅觉和边缘 - 丘脑系统的结构，以及（5） 检查相互连接的功能意义 这些前脑结构。