Mesostructure in Cat-anionic Surfactant-Polymer Films

阳离子表面活性剂聚合物薄膜中的介观结构

基本信息

批准号：
EP/H00985X/1
负责人：
Karen Edler
金额：
$ 0.67万
依托单位：
University of Bath
依托单位国家：
英国
项目类别：
Research Grant
财政年份：
2009
资助国家：
英国
起止时间：
2009 至无数据
项目状态：
已结题

来源：
https://gtr.ukri.org/projects?ref=EP%2FH00985X%2F1
关键词：
Mesostructure Cat anionic Surfactant Polymer

项目摘要

This proposal is for travel to undertake experiments using neutron reflectivity on the new instrument Platypus on the OPAL reactor at ANSTO in Sydney. It is difficult to obtain neutron reflectivity beamtime for open liquid surface samples due to the small number of instruments world-wide which are configured to take samples in this geometry and the popularity of this technique which means existing instruments are generally oversubscribed. We have succeeded in obtaining 2 days of beamtime in a competitive peer reviewed proposal scheme, on this brand new instrument, and now request travel funding to go to Sydney to carry out this experiment. The work continues our investigations into polyelectrolyte-surfactant solutions which form solid films by adsorption at the air-solution interface funded under EPSRC grant EP/E029914/1. Our initial investigations focused on the polyethylenimine-cationic surfactant system but we have now found that film formation is a general feature of solutions containing mixed aggregates of a cationic and an anionic surfactant in the presence of water soluble polymers. This enables use of biocompatible polymers which mean these films may be able to be used in enacapsulation of therapeutics for controlled delivery applications for instance in wound dressings. In this neutron reflectivity experiment we will make use of contrast variation in order to determine the proportion of each surfactant in the mesostructures of films containing CTAB and SDS with polyethylene oxide or polyacrylamide. We will investigate several different total surfactant and polymer concentrations for five CTAB:SDS ratios to study the effects on structures formed in this system. While in Sydney we have also been invited to visit Prof Greg Warr at the School of Chemistry, Sydney University to give a seminar and to observe a modified small angle X-ray scattering instrument similar to an instrument in Dr Edler's lab in Bath, with a view to implementing this modification on the Bath instrument.

该提案旨在利用悉尼 ANSTO OPAL 反应堆上的新仪器 Platypus 进行中子反射实验。由于世界范围内配置为在这种几何形状中采集样本的仪器数量很少，并且该技术的普及意味着现有仪器通常被超额认购，因此很难获得开放液体表面样品的中子反射率射束时间。我们已经在竞争性同行评审提案计划中成功获得了 2 天的光束时间，使用这个全新的仪器，现在请求旅行资金去悉尼进行这个实验。这项工作继续我们对聚电解质-表面活性剂溶液的研究，该溶液通过在空气-溶液界面吸附形成固体膜，由 EPSRC 资助 EP/E029914/1 资助。我们最初的研究集中在聚乙烯亚胺-阳离子表面活性剂体系上，但我们现在发现，成膜是在水溶性聚合物存在下含有阳离子和阴离子表面活性剂的混合聚集体的溶液的一般特征。这使得生物相容性聚合物的使用成为可能，这意味着这些薄膜可以用于治疗药物的封装，以用于受控递送应用，例如伤口敷料。在这个中子反射率实验中，我们将利用对比度变化来确定含有 CTAB 和 SDS 以及聚环氧乙烷或聚丙烯酰胺的薄膜介观结构中每种表面活性剂的比例。我们将研究五种 CTAB:SDS 比例的几种不同的总表面活性剂和聚合物浓度，以研究对该系统中形成的结构的影响。在悉尼期间，我们还受邀拜访悉尼大学化学学院的 Greg Warr 教授，举办研讨会并观察改进的小角度 X 射线散射仪器，该仪器与巴斯 Edler 博士实验室的仪器类似，具有希望在 Bath 仪器上实施此修改。