VESTIBULAR STIMULATION AND RETARDED INFANT DEVELOPMENT

前庭刺激和婴儿发育迟缓

基本信息

批准号：
3314637
负责人：
William E. MacLean
金额：
$ 9.8万
依托单位：
VANDERBILT UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
1984
资助国家：
美国
起止时间：
1984-01-01 至 1987-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/3314637
关键词：
Downs syndrome cerebral palsy child mental disorders infant human (0-1 year) mental retardation reflex disorder vestibuloocular reflex

项目摘要

Slowed motor development is a well-known phenomenon among children who suffer varied birth defects and developmental disabilities. Few treatments have been identified that will reliably and significantly enhance the motor and reflex development of disabled babies. However, recent studies indicate that specific rotational vestibular stimulation may produce positive changes in motor and reflex development among delayed infants. Preliminary evidence suggests that some preambulatory children exhibiting Down syndrome, cerebral palsy, and undifferentiated birth defects improve significantly in motor and reflex development following a regimen of semicircular canal stimulation. The purposes of this project are: (a) to study the effects of vestibular stimulation in three groups of babies (normally developing, Down syndrome, and cerebral palsy) with sample sizes sufficient to make inferences about differential responsivity to vestibular stimulation, (b) to study these babies longitudinally in order to separate treatment effects from maturational variables and to determine the long-term effects of the intervention, (c) to measure motor, reflex, physiological and cognitive functions, and (d) to study the relationship between motor development and the stereotyped movements of the babies. 20 Down syndrome, 20 cerebral palsy, and 20 normally developing preambulatory babies between .5 and 2.5 years will serve as subjects in a cross-over longitudinal design that will permit between-groups and within-subjects comparisons. The project will consist of two phases, with half of each subject population in each phase. During the second phase, the subjects will be followed at 3-month intervals to ascertain the long-term effects of the vestibular treatment. Pretest, interim, and posttest measures include motor and reflex scales, an environmental interest inventory, the Bayley Scales, parent questionnaires, and several physiological measures including postrotary nystagmus, heart rate, heart rate variability, respiration, blood pressure, weight and muscle tone. A treatment session of vestibular stimulation consists of rotating the child 10 one-minute periods of rotation in different body positions in a motorized apparatus. Sessions will be conducted 10 times over 2 weeks, on 4 different occasions during the experimental phase.

运动发育迟缓是儿童中的一个众所周知的现象患有各种出生缺陷和发育障碍。治疗次数很少已被确定将可靠且显着地增强电机和残疾婴儿的反射发育。然而，最近的研究表明特定的旋转前庭刺激可能会产生延迟婴儿运动和反射发育的积极变化。初步证据表明，一些学前儿童表现出唐氏综合症、脑瘫和未分化出生缺陷得到改善遵循以下方案，运动和反射发育显着半规管刺激。该项目的目的是： (a) 研究前庭刺激对三组婴儿的影响（正常发育、唐氏综合症和脑瘫）的样本量足以推断前庭的差异反应性刺激，（b）纵向研究这些婴儿，以便区分成熟变量的治疗效果并确定干预的长期影响，(c) 测量运动、反射、生理和认知功能，以及（d）研究其关系婴儿的运动发育和刻板动作之间的关系。 20 唐氏综合症、20 名脑瘫患者和 20 名发育正常的学前儿童 0.5 至 2.5 岁的婴儿将作为交叉实验的受试者纵向设计将允许组间和受试者内比较。该项目将分为两期，每期各占一半每个阶段的受试者人群。在第二阶段，受试者将每隔 3 个月进行一次随访，以确定其长期影响前庭治疗。预测试、中期和后测试措施包括运动和反射量表、环境兴趣量表、贝利量表、家长问卷和一些生理测量，包括旋转后眼球震颤、心率、心率变异性、呼吸、血压、体重和肌张力。前庭治疗一次刺激包括让孩子旋转 10 次，每次一分钟在机动装置中以不同身体位置旋转。会议将在 2 周内、在 4 个不同场合进行 10 次实验阶段。