The molecular basis of how cyst nematodes coordinate their life cycle with their host

胞囊线虫如何与宿主协调其生命周期的分子基础

基本信息

批准号：
BB/V00249X/1
负责人：
John Jones
金额：
$ 53.14万
依托单位：
University of St Andrews
依托单位国家：
英国
项目类别：
Research Grant
财政年份：
2021
资助国家：
英国
起止时间：
2021 至无数据
项目状态：
未结题

来源：
https://gtr.ukri.org/projects?ref=BB%2FV00249X%2F1
关键词：
molecular basis how cyst nematodes

项目摘要

Plant-parasitic nematodes cause huge damage to global agriculture. In the UK, the potato cyst nematodes (PCN) are the most important pests of potato and an absence of effective control measures for PCN causes major problems for potato growers. A key point in the PCN life cycle is a dormant survival stage - the second stage juvenile - which remains unhatched and protected in the eggs. As PCN cannot infect other crops the unhatched nematode remains dormant until chemical cues are detected from the roots of growing potato plants. In our previous work we have identified an annexin protein present in the eggshell of PCN. We have shown that this annexin is required by the nematode to maintain the normal function of the eggshell and that the protein undergoes a change in the presence of the chemical cues present in root diffusates. These data suggest that this protein plays a key role in allowing the nematode to respond to the presence of host plants. Annexins are calcium dependent lipid binding proteins. In this project we aim to determine how the annexin responds to the presence of host chemical cues and calcium to control changes in the permeability of the lipid layers in the eggshell and thus provides a link between the nematode life cycle and the presence of a host plant.

项目成果

期刊论文数量（1）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

An eggshell-localised annexin plays a key role in the coordination of the life cycle of a plant-parasitic nematode with its host.

DOI：
10.1371/journal.ppat.1011147
发表时间：
2023-02
期刊：
PLoS pathogens
影响因子：
6.7
作者：
通讯作者：

DOI：
{{ item.doi }}
发表时间：
{{ item.publish_year }}
期刊：
{{ item.journal_name }}
影响因子：
{{ item.factor }}
作者：
{{ item.authors }}
通讯作者：
{{ item.author }}

数据更新时间：{{ journalArticles.updateTime }}

作者：
{{ item.author }}

数据更新时间：{{ monograph.updateTime }}

作者：
{{ item.author }}

数据更新时间：{{ sciAawards.updateTime }}

作者：
{{ item.author }}

数据更新时间：{{ conferencePapers.updateTime }}

作者：
{{ item.author }}

数据更新时间：{{ patent.updateTime }}

John Jones其他文献

Wearables, Wearing, and the Rhetorics that Attend to Them

可穿戴设备、穿戴以及与之相关的言论

DOI：
10.1080/02773945.2016.1171689
发表时间：
2016
期刊：
Rhetoric Society Quarterly
影响因子：
0.7
作者：
Catherine C. Gouge;John Jones
通讯作者：
John Jones

Adaptive recursive Bayesian estimation using expectation maximization for respiratory motion correction in Nuclear Medicine

使用期望最大化的自适应递归贝叶斯估计用于核医学中的呼吸运动校正

DOI：
10.1109/nssmic.2013.6829066
发表时间：
2013
期刊：
2013 IEEE Nuclear Science Symposium and Medical Imaging Conference (2013 NSS/MIC)
影响因子：
0
作者：
Rhodri L. Smith;Ashrani Aizzuddin Abd. Rahni;John Jones;K. Wells
通讯作者：
K. Wells

Creating Networks Through Search - PageRank, Algorithmic Truth, and Tracing the Web

DOI：
发表时间：
2012-10
期刊：
影响因子：
0
作者：
John Jones
通讯作者：
John Jones

Inquiry in Action: Reflections on the Implementation of Best Practices in Child- and Family-Focused University–Community Partnerships

行动中的探究：对以儿童和家庭为中心的大学与社区伙伴关系实施最佳实践的思考

DOI：
发表时间：
2021
期刊：
影响因子：
0
作者：
M. Walsh;S. Adams;S. Ferguson;Mary O. Hearst;John Jones;S. Wall;Despina Petsagourakis;A. Chung;Una Shannon;Maria D. Theodorakakis
通讯作者：
Maria D. Theodorakakis