RELAPSE ONSET AND TERMINATION AND ABSTINENCE MAINTENANCE

复发发作和终止以及戒断维持

• 批准号: 2885022
• 负责人: WILLIAM H ZYWIAK
• 金额: $ 14.56万
• 依托单位: BROWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-09-03 至 2001-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2885022
• 关键词: alcoholic beverage consumption; alcoholism /alcohol abuse information system; alcoholism /alcohol abuse therapy; behavioral /social science research tag; clinical research; clinical trials; disease /disorder onset; gender difference; human data; outcomes research; perception; prognosis; psychometrics; questionnaires; racial /ethnic difference; relapse /recurrence; substance abuse epidemiology

The overarching goal of this study is to advance understanding of alcohol treatment outcome. This study will focus on four aspects of treatment outcome: 1) client perceived influences of relapse onset 2) client perceived influences of relapse termination 3) client perceived influences of periods of abstinence, and 4) temporal and alcohol-related parameters of relapse. Whereas relapse onset has received considerable attention in alcohol research, relapse termination and abstinence maintenance have received less attention. Since a data set is readily available (the Project MATCH data base; N = 1726) to do this, the cost of this study will be reduced considerably. The Relapse Questionnaire was administered in Project MATCH at the posttreatment, 6, and 12-month follow-ups. This Questionnaire consists of three sectiOns, which multidimensionally assess characteristics of relapse onset, relapse termination, and abstinence maintenance. The aims of the study are 1) to empirically determine the underlying structure of each section of this questionnaire, 2) to determine the interrelationships of temporal and alcohol-related parameters of relapse, 3) to determine the interrelationships of relapse onset, relapse termination and abstinence maintenance characteristics and the relationships of these three domains to temporal and alcohol- related parameters of relapse and general treatment outcome, 4) to determine the consistency of relapse onset, relapse termination, and abstinence maintenance over time, and to examine how consistency and changes in relapse onset and abstinence maintenance are related to treatment outcome, and 5) to examine the generalizability of the Relapse Questionnaire scales across Clinical Research Units, treatments, gender, and ethnicity. These analyses will have many implications regarding ways in which alcohol treatment can become more effective. For instance, the most dangerous relapse onset characteristics will be identified, the most efficacious abstinence maintenance methods will be identified, and the prognostic value of pretreatment relapse termination characteristics will be ascertained.

这项研究的首要目标是增进对酒精治疗结果的了解。本研究将重点关注治疗结果的四个方面：1）客户感知的复发发作的影响2）客户感知的复发终止的影响3）客户感知的禁欲期的影响，以及4）复发的时间和酒精相关参数。尽管复发的发生在酒精研究中受到了相当大的关注，但复发终止和戒酒维持却受到较少的关注。由于可以轻松获得数据集（Project MATCH 数据库；N = 1726）来执行此操作，因此本研究的成本将大大降低。复发问卷在治疗后、6 个月和 12 个月的随访中在 Project MATCH 中进行。该问卷由三个部分组成，多维度评估复发发作、复发终止和戒断维持的特征。本研究的目的是 1) 凭经验确定本问卷各部分的基本结构，2) 确定复发的时间和酒精相关参数的相互关系，3) 确定复发开始、复发终止和复发的相互关系。戒断维持特征以及这三个领域与复发的时间和酒精相关参数以及一般治疗结果的关系，4) 确定复发开始、复发终止和戒断维持的一致性时间，并检查复发发作和戒断维持的一致性和变化如何与治疗结果相关，5) 检查复发问卷量表在临床研究单位、治疗、性别和种族中的普遍性。这些分析将对如何使酒精治疗变得更有效产生许多影响。例如，将确定最危险的复发发作特征，将确定最有效的戒断维持方法，并确定治疗前复发终止特征的预后价值。