EPIDEMIOLOGIC STUDIES IN BREAST AND COLON CANCER CONTROL

乳腺癌和结肠癌控制的流行病学研究

• 批准号: 2895656
• 负责人: MARGARET MANDELSON
• 金额: $ 9.1万
• 依托单位: KAISER FOUNDATION HEALTH PLAN OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-09-06 至 2001-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2895656
• 关键词: adenomatous polyps; biomarker; biopsy; breast neoplasms; cancer prevention; cell cycle; clinical research; colon neoplasms; diagnosis design /evaluation; disease /disorder proneness /risk; endoscopy; estrogens; female; gastrointestinal imaging /visualization; hormone therapy; human middle age (35-64); human old age (65+); human subject; mammography; menopause; neoplasm /cancer epidemiology

DESCRIPTION: (Applicant's Description) This application for a Preventive Oncology Academic Award will allow the applicant to develop as an independent researcher engaged in epidemiologic studies of cancer etiology and prevention in a defined population-based, managed care setting. This application is jointly sponsored by faculty from the Center for Health Studies at Group Health Cooperative, the Cancer Prevention Research Program of the Fred Hutchinson Cancer Research Center, and the Department of Epidemiology at the University of Washington. In this setting, Dr. Mandelson plans to pursue a four-year program that consists of academic activities, post-graduate teaching, advanced training, and three research projects. Research Projects Proposed: 1. A cross-sectional study of breast cell proliferation and mammographic density in women undergoing excisional breast biopsy. 2. An evaluation of mammography performance in elderly women. 3. A case-control study of hormone replacement therapy and adenomatous polyps. This plan is focused on three specific areas of interest: the use of biomarkers in cancer epidemiology research, cancer screening evaluation, and cancer etiology. Completion of this program will provide a strong foundation for a successful independent career in cancer control research.

描述：（申请人的描述）本申请为预防性措施 肿瘤学学术奖将使申请人能够发展为 从事癌症病因流行病学研究的独立研究员 以及在特定的以人群为基础的管理式护理环境中进行预防。 这 申请由健康中心的教师联合赞助 团体健康合作社、癌症预防研究计划的研究 弗雷德哈钦森癌症研究中心和部门 华盛顿大学流行病学。 在这种背景下，博士。 曼德尔森计划攻读一个为期四年的项目，其中包括学术 活动、研究生教学、进修、三项研究 项目。 拟议的研究项目： 1. 横断面研究 女性乳腺细胞增殖和乳房 X 光密度 切除乳房活检。 2.老年女性乳房X线摄影表现的评估。 3. 激素替代治疗与腺瘤的病例对照研究 息肉。 该计划重点关注三个特定领域： 癌症流行病学研究、癌症筛查评估中的生物标志物 癌症病因学。 该计划的完成将为成功提供坚实的基础 癌症控制研究的独立职业。