DETECTION AND RISK OF EHRLICHIAL DISEASES

埃利希病的检测和风险

• 批准号: 2447201
• 负责人: RICHARD C FALCO
• 金额: $ 7.4万
• 依托单位: FORDHAM UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-03-01 至 2001-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2447201
• 关键词: Ixodes; Rickettsiales disease; animal population study; arthropod borne communicable disease; communicable disease diagnosis; disease /disorder proneness /risk; dogs; immunofluorescence technique; microorganism culture; polymerase chain reaction; serology /serodiagnosis; ticks

DESCRIPTION (adapted from applicant's abstract): Human granulocytic ehrlichiosis (HGE) and human monocytic ehrlichiosis (HME) are emerging tick-borne disease in the U.S. Annual incidence of both disease is increasing, with more than 600 cases of human ehrlichiosis reported in the last ten years. The purpose of this study is to detect the presence and distribution of the HGE agent and related ehrlichial pathogens in New York State. Specifically, the applicant will evaluate the utility of canine serology to assess risk for HGE in an endemic area, 2) measure canine seroprevalence in areas where few or no cases of HGE are reported, 3) test Ixodes scapularis and Amblyomma americanum for the presence of Ehrlichia species and related pathogens, and 4) establish a canine serum bank and a tick depository for future retrospective studies on emerging tick-borne diseases in the region.

描述（改编自申请人的摘要）：人类粒细胞 埃利希体病 (HGE) 和人单核埃利希体病 (HME) 正在出现 在美国，两种疾病的年发病率为 不断增加，据报告，人类埃利希体病病例已超过 600 例 过去十年。 本研究的目的是检测其存在并 HGE 病原体和相关埃利希体病原体在纽约的分布 状态。 具体来说，申请人将评估犬类的效用 血清学评估流行地区 HGE 风险，2) 测量犬类 很少或没有报告 HGE 病例的地区的血清阳性率，3) 检测 肩胛硬蜱和美洲钝蜱用于检测埃里希体的存在 物种和相关病原体，4）建立犬血清库和 蜱虫保藏库，用于未来对新出现的蜱传疾病进行回顾性研究 该地区的疾病。