PSYCHOPATHOLOGY AND COURSE OF RECURRENT ABDOMINAL PAIN

复发性腹痛的精神病理学和病程

• 批准号: 2897292
• 负责人: John Vincent Campo
• 金额: $ 14.97万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-09-20 至 2004-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2897292
• 关键词: abdomen; adolescence (12-20); anxiety; behavioral /social science research tag; clinical research; curriculum; functional ability; health services research tag; human subject; injury /disease stressor; interview; longitudinal human study; middle childhood (6-11); pain; parent offspring interaction; patient care management; pediatrics; personality; psychological stressor; psychosomatic disorders; relapse /recurrence; social competition; training

The career development and research plans outlined in this Mentored Patient-Oriented Research Career Development Award application are designed to enable the candidate to independently design and conduct studies of pediatric current abdominal pain (RAP), its course, and associated psychopathology relevant to the design of future clinical interventions. RAP is defined as at least three episodes of medically unexplained abdominal pain occurring over a period of at least three months that are severe enough to affect the activities of the child. RAP is common, impairing, and puts children at risk for dangerous, costly, and unnecessary medical procedures. Previous studies of RAP and associated psychopathology have not employed standardized psychiatric interviews and longitudinal designs, and are confounded by tertiary referral bias. Understanding the relationship of RAP and its course with anxiety, depression, and other risk factors will prepare the way for the development of effective intervention and prevention strategies, as well as family and psychobiological studies. The proposed study of RAP is the first to employ standardized psychiatric interviews and a longitudinal design in pediatric primary care, and will compare RAP presenters with unaffected children on measures of psychopathology, temperament, other somatic symptoms, life events, and parental psychopathology, health, and encouragement of illness behavior, providing the candidate experience in the conduct of longitudinal studies and the use of modern research assessments. The candidate is certified in pediatrics, psychiatry, and child and adolescent psychiatry, with nearly ten years of post-graduate clinical experience. Dr. David Brent will serve as preceptor. Course work and directed readings in epidemiology, biostatistics, data management, research ethics, the neurobiology of brain-gut interactions, neuropharmacology, drug development, and the design of psychopharmacologic and psychotherapeutic clinical trials will complement the research training.

该指导的注重患者的研究职业发展奖的职业发展和研究计划旨在使候选人能够独立设计和进行针对儿科当前腹痛（RAP）的研究，其课程以及与设计有关的心理病理学与设计有关未来的临床干预措施。 RAP被定义为至少三个月内发生的三个月的腹痛至少三个月，至少三个月严重，足以影响儿童的活动。 说唱很常见，损害，并使儿童有危险，昂贵和不必要的医疗程序的风险。 先前关于RAP和相关心理病理学的研究尚未采用标准化的精神病访谈和纵向设计，并且被第三级推荐偏见混淆。 了解说唱的关系及其与焦虑，抑郁和其他风险因素的关系将为开发有效的干预和预防策略以及家庭和心理生物学研究的发展做准备。 拟议的RAP研究是第一个在儿科初级保健中采用标准化精神病访谈和纵向设计的研究，并将在心理病理学，气质，其他躯体症状，生活事件和父母精神病理学，健康，健康，健康，健康，健康，健康，健康，健康，生活，生活，生活，生活，生活，生活，生活，生活，生活，其他，健康，生活，其他，健康，生活，健康，生活，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，健康，将在儿科初级保健中进行了纵向设计。并鼓励疾病行为，提供纵向研究和使用现代研究评估的候选经验。 该候选人获得儿科，精神病学以及儿童和青少年精神病学的认证，并拥有近十年的研究生临床经验。 戴维·布伦特（David Brent）博士将担任主持人。 课程工作和流行病学，生物统计学，数据管理，研究伦理学，脑胰型相互作用的神经生物学，神经药理学，药物开发以及心理药理学和心理治疗临床试验的设计将补充研究培训。