HYDRODYNAMIC THRUST BEARING FOR BLOODPUMPS

血泵流体动力推力轴承

• 批准号: 2716925
• 负责人: HOOSHANG HESHMAT
• 金额: $ 9.37万
• 依托单位: MOHAWK INNOVATIVE TECHNOLOGY, INC.
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-07-15 至 1999-08-15
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2716925
• 关键词: auxiliary heart prosthesis; bioengineering /biomedical engineering; biomaterial development /preparation; biomaterial interface interaction; biomedical equipment development; biotechnology; circulatory assist; clinical biomedical equipment; hemodynamics; hemolysis; implant; mathematical model; mechanical stress

The ultimate objective of this program is to develop a hydrodynamic thrust bearing for use in a wide range of continuous flow implantable rotary blood pumps. Development and integration of the MiTi hydrodynamic thrust bearing into rotary blood pumps will enhance overall reliability of this life support system. The proposed development will result in a hydrodynamic thrust bearing design capable of sharing load with pumps such as those that employ pivot bearings reducing friction induced thrombosis. The developed bearing will also be suitable for use with magnetic bearing systems to limit rotor motions in the event of a shock transient or in the event of a catastrophic failure of the active magnetic bearing. During the Phase I effort, l) a parametric thrust bearing design study will be conducted for a nominal 5 liter/min pump; 2) a detailed design of a thrust bearing that minimizes blood shear stresses, ensures good wash flows and can sustain expected steady state and dynamic shock loads will be completed; 3) the designed bearing will be fabricated; 4) two series of tests simulating the expected blood pump environment will be conducted including a final test series at the CCF to assess the potential for any detrimental hemolysis occurring due to passage through the bearing and 5) a final report including the Phase II plan will be established to complete the effort. The key benefit of this effort is the development of a robust bearing to enhance the reliability of rotoray bloodpumps in a simple passive configuration. PROPOSED COMMERCIAL APPLICATIONS: Applications include short duration clinical use and long term implantable bloodpumps in a simple, robust and cost effective package. Estimates are that anywhere from 35,000 to 200,000 patients a year could benefit from an implantable ventricular assist device if one were available.

该计划的最终目标是开发流体动力 推力轴承可用于多种连续流动植入 旋转血泵。 MITI流体动力学的开发和整合 旋转血泵的推力轴承将提高总体可靠性 这一生命支持系统。拟议的发展将导致 流体动力推力轴承设计能够与泵共享负载 例如那些使用枢轴轴承减少摩擦诱导的轴承 血栓形成。开发的轴承也适合与 磁性轴承系统在发生冲击时限制转子运动 瞬态或有效的灾难性失败 磁性轴承。在第一阶段的努力中，l）参数推力 轴承设计研究将用于标称5升/分钟泵的轴承； 2）推力轴承的详细设计可将血剪切降至最低 压力，确保良好的洗涤流量并可以维持预期的稳态 和动态冲击负荷将完成； 3）设计的轴承将 被捏造； 4）两个模拟预期血泵的一系列测试 环境将进行，包括CCF的最终测试系列 评估由于 通过轴承和5）最终报告，包括II期 将制定计划来完成努力。 这项努力的关键好处是发展强大的方面 在简单的被动中增强rotoray holdopumps的可靠性 配置。 拟议的商业应用： 应用包括短期临床用途和长期使用 简单，健壮且具有成本效益的包装中可植入的血液泵。 估计是，每年从35,000至200,000名患者可以 如果一个人受益于植入的心室辅助装置 可用的。

项目成果

Performance characterization of a rotary centrifugal left ventricular assist device with magnetic suspension.

磁悬浮旋转离心式左心室辅助装置的性能表征。

• DOI: 10.1111/j.1525-1594.2008.00559.x
• 发表时间: 2008
• 期刊: Artificial organs
• 影响因子: 2.4
• 作者: Jahanmir,Said;Hunsberger,AndrewZ;Heshmat,Hooshang;Tomaszewski,MichaelJ;Walton,JamesF;Weiss,WilliamJ;Lukic,Branka;Pae,WilliamE;Zapanta,ConradM;Khalapyan,TigranZ
• 通讯作者: Khalapyan,TigranZ