CARCINOGENESIS MODELING AND RISK ASSESSMENT

致癌建模和风险评估

• 批准号: 2595964
• 负责人: DONALD L THOMSEN
• 金额: $ 0.7万
• 依托单位: SOCIETAL INSTITUTE OF THE MATH SCIENCES
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-04-01 至 1999-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2595964
• 关键词: cancer risk; carcinogenesis; meeting /conference /symposium; travel

DESCRIPTION: (Applicant's Description) Stochastic modeling in carcinogenesis studies has been used in recent years to address critical issues associated with genesis, management and follow-up of cancer. Much of this effort has been stimulated by observations on morbidity and mortality in populations or observations at t he cellular level in mammalian systems. However, with the radical pace at which cancer biology is advancing our understanding of t he carcinogenic process, these models need to be evaluated for currency and challenged to include information from modern biology. The purpose of this workshop is to bring together quantitative and biological scientists in a forum to stimulate advances in the mathematical modeling of carcinogenesis. Biological talks will focus on the current theories of how cancers develop and process. Quantitative talks will focus on the state-of-the-art in cancer modeling and some of the limitations existing under current experimental findings. Ample opportunity will be given for both groups of scientists to carefully define terms allowing for a more thorough discussion of the concepts.

描述：（申请人的描述）随机建模 近年来，致癌作用研究已被用来解决 与起源、管理和后续行动相关的关键问题 癌症。 这项努力的大部分是由对以下问题的观察刺激的： 人群的发病率和死亡率或细胞观察 哺乳动物系统中的水平。 然而，随着 癌症生物学正在增进我们对致癌物质的理解 过程中，这些模型需要进行货币评估并受到挑战 包括来自现代生物学的信息。 这样做的目的 研讨会旨在将定量和生物科学家聚集在一起 促进数学建模进步的论坛 致癌作用。 生物学讲座将集中于当前的理论 癌症如何发展和过程。 定量讨论将集中于 癌症建模的最新技术和现有的一些局限性 根据目前的实验结果。 将给予充足的机会 让两组科学家仔细定义术语，以便 对概念进行更深入的讨论。