BREAST CANCER SURVEILLANCE RESEARCH IN NEW MEXICO

新墨西哥州乳腺癌监测研究

• 批准号: 2113936
• 负责人: CHARLES R. KEY
• 金额: $ 37.99万
• 依托单位: UNIVERSITY OF NEW MEXICO
• 依托单位国家: 美国
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-09-30 至 2000-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2113936
• 关键词: Hispanic Americans; Native Americans; biopsy; breast neoplasm /cancer diagnosis; breast neoplasms; cancer information system; cancer registry /resource; cancer risk; community health services; cooperative study; diagnosis quality /standard; early diagnosis; female; health behavior; health care service utilization; human subject; mammary disorder; mammography; managed care; mass screening; molecular oncology; neoplasm /cancer epidemiology; population survey; prognosis; rural area

While screening mammography in controlled trials is capable of decreasing breast cancer mortality by 30%, its effectiveness, Costs, and utilization in rural and ethnically diverse Communities is not known. We propose to create a geographically defined, population-based resource in the state of New Mexico, a multi-ethnic and largely rural state. The resource will include complete ascertainment of screening mammograms, breast cancers, and benign breast tumors, and a population-based survey of breast cancer risk factors and screening behaviors in screened and unscreened women. This resource will allow analytic and descriptive studies of the following aspects of screening mammography: 1) differences in outcomes, performance, and utilization in rural vs. urban and among different ethnic populations, 2) radiologic, pathologic and molecular differences in cancers detected by screening and cancers missed by screening, 3) screening costs in the region's largest HMO, including costs of subsequent treatment as a function of stage at diagnosis, and 4) an intervention project using lay health advisors to increase screening rates in a rural and largely Hispanic region in northern New Mexico. The core of the proposed study is the expansion of the Albuquerque metropolitan area surveillance system (established as a pilot study by the New Mexico Tumor Registry in 1990) to include complete coverage of the state's rural areas. This resource consists of mammogram data, benign breast biopsy data, and incident breast cancer data. Linkage of these three data bases allows calculation of mammography sensitivity, positive predictive value, and stage at diagnosis distribution of mammography- detected cancers. We propose to collect electronic data on all mammograms performed in the state of New Mexico, data on all benign and malignant breast biopsies, and data on quality assurance and image quality for radiology groups. Surveillance data for the entire population of women at risk for breast cancer will be augmented by a population-based telephone survey concerning screening knowledge, attitudes, and behaviors that will include women who are and who are not undergoing screening mammography. This resource will provide a unique opportunity to examine screening mammography performance in Hispanics, American Indians, and non-Hispanic whites residing in rural and underserved populations.

在对照试验中筛选乳房X线摄影能够减少 乳腺癌死亡率增加了30％，其有效性，成本和利用率 在农村和种族多元化的社区中，尚不清楚。我们建议 在该州创建一个以地理定义的，基于人群的资源 新墨西哥州，一个多种族，主要是农村国家。资源将 包括完全确定筛查乳房X线照片，乳腺癌， 和良性乳腺肿瘤，以及基于人群的乳腺癌调查 筛查和未经筛查的妇女中的危险因素和筛查行为。 该资源将允许对 筛查乳房X线摄影的以下各个方面：1）结局的差异， 绩效和农村与城市的利用 种族人群，2）放射学，病理和分子差异 在通过筛查检测到的癌症中，筛查错过的癌症，3） 该地区最大的HMO筛查成本，包括 随后的治疗作为诊断阶段的函数，4） 使用外行健康顾问进行干预项目来增加筛查 在新墨西哥州北部的农村和西班牙裔地区的农村和西班牙裔地区的比率。 拟议研究的核心是阿尔伯克基的扩展 大都市地区监视系统（由试点研究成立 1990年的新墨西哥肿瘤注册中心）包括 该州的农村地区。该资源由乳房X线图数据，良性组成 乳房活检数据和事件乳腺癌数据。这些联系 三个数据基础允许计算乳房X线摄影敏感性，阳性 预测价值，乳房X线摄影的诊断分布阶段 - 检测到的癌症。我们建议收集所有乳房X线照片的电子数据 在新墨西哥州表演，所有良性和恶性的数据 乳房活检，以及有关质量保证和图像质量的数据 放射学组。整个妇女人口的监视数据 乳腺癌的风险将被基于人群的 有关筛查知识，态度和行为的电话调查 这将包括那些正在筛查的妇女 乳房X线摄影。该资源将提供一个独特的机会来检查 在西班牙裔，美国印第安人和 居住在农村和服务不足的人群中的非西班牙裔白人。