Developmental Research Program

发展研究计划

• 批准号: 10555405
• 负责人: GLENN LIU
• 金额: $ 12.6万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10555405
• 关键词: Area; Basic Science; Budgets; Caliber; Cancer Biology; Cancer Center; Clinical; Clinical Trials; Collaborations; Communities; Development; Direct Costs; Disease Outcome; Early Diagnosis; Ensure; Faculty; Feedback; Funding; Future; Grant; Guidelines; Institution; Investigator-Initiated Research; Laboratories; Malignant neoplasm of prostate; Minority Groups; Mission; Monitor; Morbidity - disease rate; Patients; Peer Review; Phase; Population; Prevention; Process; Prognostic Marker; Program Research Project Grants; Prostate; Publications; Recommendation; Research; Research Personnel; Resources; Rewards; Schools; Stream; Thinking; Translational Research; Treatment outcome; Underrepresented Minority; United States National Institutes of Health; Universities; Update; Wisconsin; Work; career; high reward; high risk; improved outcome; innovation; insight; meetings; mortality; multidisciplinary; predictive marker; programs; research study; survivorship; translational goal

PROJECT SUMMARY The University of Wisconsin Prostate Cancer SPORE Developmental Research Program (DRP) supports early- phase projects that have the potential to open new areas of translational research opportunity, and lead to reduced morbidity and mortality in patients with prostate cancer. Developmental projects include research focused on basic science discoveries, prevention, early detection, treatment, development of prognostic and predictive biomarkers, as well as survivorship. The DRP provides pilot funding to support innovative and high- impact research in prostate cancer and will solicit, advise, review, select, and monitor DRP projects to ensure that DRP resources are effectively used. The Specific Aims for the Developmental Research Program are to: 1. Stimulate creation of multi-disciplinary teams to conduct impactful research studies in prostate cancer that include basic, clinical, and population researchers, as well as collaboration with outside SPORE institutions and investigators. 2. Provide 1-2 years of funding to support investigator-initiated research that may lead to subsequent grants, clinical trials, or insight on project feasibility, as well as become a future SPORE project. 3. Support high-risk, high-reward ideas that may be too early for traditional grant mechanisms but deemed innovative and important to explore. 4. Monitor progress of funded DRP projects and recommend which projects should be advanced to a full SPORE project.

项目概要 威斯康星大学前列腺癌 SPORE 发展研究计划 (DRP) 支持早期- 阶段项目有可能开辟新的转化研究机会领域，并导致 降低前列腺癌患者的发病率和死亡率。开发项目包括研究 专注于基础科学发现、预防、早期检测、治疗、预后和发展 预测生物标志物以及生存率。 DRP 提供试点资金以支持创新和高 影响前列腺癌的研究，并将征求、建议、审查、选择和监督 DRP 项目，以确保 DRP 资源得到有效利用。 发展研究计划的具体目标是： 1. 鼓励建立多学科团队，对前列腺癌进行有影响力的研究 其中包括基础、临床和群体研究人员，以及与外部 SPORE 的合作 机构和调查人员。 2. 提供 1-2 年的资金支持研究者发起的研究，这些研究可能会带来后续资助， 临床试验，或对项目可行性的见解，以及成为未来的 SPORE 项目。 3. 支持高风险、高回报的想法，这些想法对于传统资助机制来说可能为时过早，但被认为是 创新且值得探索。 4. 监控受资助的 DRP 项目的进展情况，并建议哪些项目应全面推进 孢子项目。