HEPATITIS AND AIDS RESEARCH

肝炎和艾滋病研究

• 批准号: 3646085
• 负责人: WILLIAM J. GOODWIN
• 金额: $ 51.9万
• 依托单位: TEXAS BIOMEDICAL RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-06-18 至 1992-06-17
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3646085
• 关键词: AIDS; Pan; animal colony; disease /disorder model; health science research; hepatitis B

The Contractor shall maintain a colony of forty-nine (49) NHLBI-owned chimpanzees that are available for research on posttransfusion viral hepatitis or AIDS. Proposals to utilize these animals are initiated by the scientific community and reviewed for scientific merit and program relevance by NHLBI Staff and a PHS AIDS Animal Model Committee. Chimpanzees are made available for approved research under a separate contract between the user and the contractor. Laboratory and technical support will also be provided under this separate contract.

承包商应维持由四十九 (49) 只 NHLBI 拥有的殖民地 可用于研究输血后病毒的黑猩猩 肝炎或艾滋病。 利用这些动物的提议是由 科学界并对其科学价值和计划进行审查 NHLBI 工作人员和 PHS 艾滋病动物模型委员会的相关性。 黑猩猩可用于根据单独的批准研究 用户与承包商之间的合同。 实验室和技术 还将根据这份单独的合同提供支持。

项目成果

Inguinal hernial surgery in an infant chimpanzee.

黑猩猩幼崽的腹股沟疝气手术。

• 发表时间: 1989
• 期刊: Journal of medical primatology
• 影响因子: 0.7
• 作者: Taylor,AF;Smith,M;Eichberg,JW
• 通讯作者: Eichberg,JW

Photochemical decontamination of blood components containing hepatitis B and non-A, non-B virus.

对含有乙型肝炎和非甲非乙病毒的血液成分进行光化学净化。

• DOI: 10.1016/s0140-6736(88)90931-2
• 发表时间: 1988
• 期刊: Lancet (London, England)
• 作者: Alter,HJ;Creagan,RP;Morel,PA;Wiesehahn,GP;Dorman,BP;Corash,L;Smith,GC;Popper,H;Eichberg,JW
• 通讯作者: Eichberg,JW

Antibody-dependent enhancement of human immunodeficiency virus type 1 (HIV-1) infection in vitro by serum from HIV-1-infected and passively immunized chimpanzees.

• DOI: 10.1073/pnas.86.12.4710
• 发表时间: 1989-06
• 期刊: Proceedings of the National Academy of Sciences of the United States of America
• 影响因子: 11.1
• 作者: W. Robinson;D. Montefiori;W. Mitchell;A. Prince;H. Alter;G. Dreesman;J. Eichberg

Evaluation of a chimpanzee colony for antibodies to hepatitis C virus.

评估黑猩猩群体的丙型肝炎病毒抗体。

• DOI: 10.1002/jmv.1890340303
• 发表时间: 1991
• 期刊: Journal of medical virology
• 影响因子: 12.7
• 作者: Lanford,RE;Notvall,L;Barbosa,LH;Eichberg,JW
• 通讯作者: Eichberg,JW

Synthetic peptides define the fine specificity of the human immunodeficiency virus (HIV) gp160 humoral immune response in HIV type 1-infected chimpanzees.

合成肽定义了 1 型 HIV 感染黑猩猩中人类免疫缺陷病毒 (HIV) gp160 体液免疫反应的精细特异性。

• DOI: 10.1128/jvi.64.2.486-492.1990
• 发表时间: 1990
• 期刊: Journal of virology
• 影响因子: 5.4
• 作者: Warren,RQ;Wolf,H;Shuler,KR;Eichberg,JW;Zajac,RA;Boswell,RN;Kanda,P;Kennedy,RC
• 通讯作者: Kennedy,RC