Administrative Core

行政核心

• 批准号: 10556889
• 负责人: JENNIFER H ELISSEEFF
• 金额: $ 8.84万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-01 至 2026-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10556889
• 关键词: Adoption; Advisory Committees; Aging; Atlases; Benchmarking; Biological; Cataloging; Collaborations; Communication; Computer Analysis; Data; Data Analyses; Data Coordinating Center; Data Management Resources; Data Set; Data Storage and Retrieval; Development; Ensure; Evaluation; Generations; Goals; Image; Immunology; Institution; Leadership; Length; Longevity; Mus; Procedures; Process; Protocols documentation; Quality Control; Recording of previous events; Reporting; Research Personnel; Site; Specimen; Standardization; Structure; System; Technology; Testing; Tissues; United States National Institutes of Health; Work; analysis pipeline; arm; big data management; computerized data processing; conflict resolution; experience; interest; internal control; meetings; mouse genetics; new technology; operation; programs; response; senescence; sex; single-cell RNA sequencing; tissue mapping

The Administrative Core will provide the governance and coordination structure to spearhead the Atlas generation in the JMN-MSMP. The Administrative Core will coordinate and integrate the Biological Analysis Core (BAC) and Data Analysis Core (DAC), and will ensure harmonization of processes and quality control within the JMN-MSMP and with the SenNet Consortium Organization and Data Coordination Center (CODCC) to provide standardized, high-quality datasets for Atlas generation. The MPIs will engage all key stakeholders in shared governance to ensure that perspectives from all components are considered. This will be achieved through an Executive Committee (EC) consisting of the MPIs, and Core Leaders. The AC will coordinate monthly meetings of the EC to review operations, benchmarks, and metrics for continuous quality improvement; provide a forum to introduce emerging opportunities of interest; and formulate action plans for a coordinated response. Internal and External Advisory Committees will provide regular, expert, arms-length advice on scientific decisions, review progress, and assist with conflict resolution. The Administrative Core will work closely with the NIH program manager and external TMCs and data coordinating centers to communicate processes and datasets. Aim 1. Provide JMN-MSMP interdisciplinary leadership and governance structure. Aim 2. Oversee and Coordinate the Biological Analysis and Data Analysis Cores. Aim 3. Coordinate with other SenNet sites to standardize operations and protocols; and prepare, organize, and maintain JMN-MSMP reports and Atlas development.

行政核心将提供治理和协调结构，以带头 JMN-MSMP 中的 Atlas 一代。行政核心将协调和整合 生物分析核心（BAC）和数据分析核心（DAC），并将确保协调一致 JMN-MSMP 和 SenNet 联盟内的流程和质量控制 组织与数据协调中心（CODCC）提供标准化、高质量 用于 Atlas 生成的数据集。 MPI 将让所有主要利益相关者参与共同治理，以 确保考虑所有组成部分的观点。这将通过一个 执行委员会 (EC) 由 MPI 和核心领导人组成。审计委员会将协调 EC 每月举行一次会议，审查运营、基准和持续质量指标 改进;提供一个论坛来介绍新出现的感兴趣的机会；并制定 协调应对的行动计划。内部和外部咨询委员会将提供 就科学决策提供定期、专家、公平的建议、审查进展情况并协助 冲突解决。行政核心将与 NIH 项目经理密切合作， 外部 TMC 和数据协调中心来交流流程和数据集。 目标 1. 提供 JMN-MSMP 跨学科领导和治理结构。 目标 2. 监督和协调生物分析和数据分析核心。 目标 3. 与其他 SenNet 站点协调以标准化操作和协议；和 准备、组织和维护 JMN-MSMP 报告和 Atlas 开发。