CARDIOVASCULAR HEALTH STUDY--ECHOCARDIOGRAPHY

心血管健康研究--超声心动图

• 批准号: 2313581
• 负责人: JOHN S. GOTTDIENER
• 金额: $ 9.31万
• 依托单位: GEORGETOWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1993
• 资助国家: 美国
• 起止时间: 1993-06-30 至 2000-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2313581
• 关键词: CARDIOVASCULAR; HEALTH; STUDY; ECHOCARDIOGRAPHY

The primary objective of this study is to investigate the risk factors for coronary heart disease (CHD) and stroke in the elderly (aged 65+). Both risk factors established in middle-aged populations and suspected risk factors will be examined. Since atherosclerosis is prevalent in the elderly, the study will focus on factors thought to induce clinically overt disease. It will do so in two ways: 1) it will assess the prediction of clinical disease from measures of preclinical disease, such as carotid atherosclerosis, left ventricular impairment, and arrhythmias or episodes of myocardial ischemia. 2) Since cardiovascular events may occur in elderly people as a result of health or life circumstances which may have changed in the months preceding the event, the study will contact participants at frequent intervals to evaluate their status with respect to concurrent disease, social support networks, stressful life situations, diet, physical activity and other risk factors. The study has three secondary objectives pertaining to the elderly populations: 1) to evaluate the factors associated with preclinical cardiovascular diseases (such as carotid atherosclerosis, left ventricular impairment and episodes of arrhythmia or myocardial ischemia); 2) to evaluate predictors of disability, institutionalization and mortality to participants who have CHD or stroke; and 3) to measure the utilization and impact of medical care services for CHD and stroke. The contractor shall serve as the Echocardiography Reading Center. The duties of the Center include protocol development, instruction and supervision of CHS Field Centers in performance of echocardiography; measurement of parameters; and analysis and publication of data.

这项研究的主要目的是调查风险因素 对于老年人（65岁以上）的冠状动脉疾病（CHD）和中风。 在中年人口中建立的两个风险因素，并怀疑 将检查风险因素。 由于动脉粥样硬化在 老年人，该研究将集中于被认为诱导临床诱导的因素 公开疾病。 它将以两种方式这样做：1）它将评估 通过临床前疾病的措施预测临床疾病， 如颈动脉粥样硬化，左心室障碍和心律不齐 或心肌缺血的情节。 2）由于心血管事件可能 由于健康或生活状况而发生的老年人 在活动之前的几个月中可能发生了变化，研究将 经常与参与者联系以评估其状态 尊重并发疾病，社会支持网络，压力很大的生活 情况，饮食，体育锻炼和其他危险因素。 该研究有三个与老年人有关的次要目标 人群：1）评估与临床前有关的因素 心血管疾病（例如颈动脉粥样硬化，左 心律失常或心肌情节的心室障碍和发作 缺血）; 2）评估残疾，制度化的预测因素 对患有CHD或中风的参与者的死亡； 3）测量 医疗服务对CHD和中风的利用和影响。 承包商应作为超声心动图阅读中心。 这 该中心的职责包括协议开发，指导和 超声心动图表现的CHS现场中心的监督； 参数的测量；以及数据的分析和发布。