PREPARATION OF ANTIAIDS BULK DRUGS AND CHEMICALS

抗艾滋病原料药和化学品的制备

• 批准号: 2300513
• 负责人: JACK J PARSONS
• 金额: $ 50.86万
• 依托单位: STARKS ASSOCIATES, INC.
• 依托单位国家: 美国
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-09-30 至 1997-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2300513
• 关键词: antiAIDS agent; chemical registry /resource; drug design /synthesis /production; drug quality /standard

The project is for the preparation of known chemicals and bulk drugs which are needed by the Program for toxicology, pharmacology and clinical use. The compounds selected for preparation are not readily available in the quality or quantities required from the original supplier or on the open market. This project is part of the DTP's program to procure bulk chemicals and drugs for the treatment of AIDS. This project provides the means to obtain nearly any type of chemical compound and the ability to provide large quantities or very high purity drugs. Assignments of materials for preparation will originate with the Pharmaceutical Resources Branch. Many of the preparations will involve a wide variety of chemical structures. Many of the preparations will involve multi-step sequences and all materials prepared will be fully characterized. Solubility and stability studies and cost data will be provided upon request.

该项目为已知化学品及原料药制备 该计划需要毒理学、药理学和临床 使用。 所选用于制备的化合物不容易在 原始供应商或供应商要求的质量或数量 开放市场。 该项目是 DTP 批量采购计划的一部分 用于治疗艾滋病的化学品和药物。 该项目提供了获取几乎任何类型化学品的方法 化合物以及提供大量或极高纯度的能力 药物。 准备材料的分配将由 医药资源分会。 许多准备工作将涉及 化学结构多种多样。 许多准备工作将 涉及多步骤顺序，所有准备的材料都将充分 特点。 溶解度和稳定性研究以及成本数据将 根据要求提供。