2022-2024 US DOHaD Society Meetings

2022-2024 美国 DOHaD 协会会议

基本信息

批准号：
10538688
负责人：
PHU V. TRAN
金额：
$ 1.3万
依托单位：
UNIVERSITY OF MINNESOTA
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-07-01 至 2025-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10538688
关键词：
Advocate Alcohols American Area Australia Award Awareness Biological Markers Biomedical Research COVID-19 pandemic Child Development Choline Chronic Disease Cities Collaborations Data Development Developmental Biology Disease Elderly Endocrine Disruptors Endocrinology Ensure Environment Environmental Exposure Epidemiologist Epidemiology Ethnic Origin Event Exposure to Faculty Fellowship Fetal Development Folic Acid Fostering Funding Future Gender Generations Goals Government Government Agencies Grant Health Heat Stress Disorders Hormones Human Development Hybrids Individual Industry Institution International Intervention Investigation Kansas Knowledge Lactation Lead Leadership Life Life course epidemiology Long-Term Effects Longevity Malignant Neoplasms Mammals Measures Medical Methodology Michigan Minnesota Minority Minority Groups Minority Recruitment Mission National Institute of Environmental Health Sciences Netherlands Newborn Infant North Carolina Nutrient Nutritionist Outcome Participant Pathology Pediatric Hospitals Perinatal Persons Pharmaceutical Preparations Pharmacologic Substance Physicians Postdoctoral Fellow Pregnancy Prevention strategy Public Health Applications Research Public Policy Research Research Methodology Research Personnel Risk Role Science Scientist Singapore Societies Source South Africa Stress Students Surveys Toxic Environmental Substances Toxicology Training Travel Underrepresented Minority Underserved Population United States United States National Institutes of Health Universities Woman Writing career career development coronavirus disease cost disorder risk diversity and inclusion environmental chemical environmental chemical exposure environmental toxicology epigenomics exosome experience fetal gender minority graduate student gut microbiota improved indexing interest maternal microbiota meetings microbiome multidisciplinary novel nutrition offspring pathogen pre-doctoral prevent programs recruit sex societal costs sound stressor success symposium toxicant virtual

项目摘要

ABSTRACT The fundamental concept of Developmental Origins of Health and Diseases (DOHaD), which posits that early- life events or exposures determine the health outcomes across the life span, has been well represented by the US DOHaD Society exemplified by its annual national meeting since its inception in 2016. Its annual meeting brings together investigators with diverse backgrounds who otherwise may not likely interact, including those researching in the areas of developmental biology, life course epidemiology, nutrition, environmental toxicology, cancer, stress, and endocrinology. Such individuals span institutions across the US from universities to industry to government agencies (NIH, EPA, NIEHS) to share knowledge and recent advancements on how environmental toxicants, nutrients, pharmaceutical agents, pathogens, gut microbiota, stress, and emerging factors influence developing fetuses and newborns, and thereby contribute to their health and disease across the life span. Further, presentations also delve into how such factors might lead to harmful effects in the subsequent generations, i.e., transgenerational effects. The major goal of the US DOHaD Society’s annual meeting is to foster multidisciplinary interactions and promote collaborations on these diverse topics. The second objective is to provide opportunity for trainees (graduate students, postdoctoral fellows, and junior faculty) to interact with world-renown experts, facilitating the development of future scientists and career opportunities in the field. The third objective is to continue promoting diversity, inclusivity, and equal representation of sex, gender and underrepresented minority groups as speakers and session leaders. Notably, women and minority represented >50% and >20% speakers and moderators, respectively, over the last five meetings. The past five conferences have been enormously successful, particularly the 2021 hybrid (in-person and virtual) meeting despite the ongoing COVID pandemic. Such successes provide impetus for continued and permanent annual meetings. The 6th, 7th, and 8th Annual Meetings will again be a hybrid format and held at the University of Minnesota (Minneapolis, 2022), the Mercy’s Children Hospital (Kansas City, 2023) and the Rizzo Center (Chapel Hill, 2024), respectively. The theme for the 2022 meeting will be “Environmental Exposures: Assessment Methodologies, Mechanisms, and Health Outcomes”. Analogous to the 2021 meeting, the program will include a dedicated day on career development and grant writing that will be provided in kind to all trainees. Preliminary themes for 2023 and 2024 will cover topics including maternal microbiota and child development, exosomes as carriers of biomarkers, effects of maternal supplemental folate, choline and DHA on offspring health outcomes associated with epigenomic changes, and epidemiological analyses of long-term health outcomes associated with heat stress during pregnancy and lactation. In short, the strength of the U.S. DOHaD Society lies in its diversity in terms of the research it represents and those researching these areas.

抽象的健康与疾病的发育起源（DOHaD）的基本概念，它假设早期- 生活事件或暴露决定了整个生命周期的健康结果，这一点已得到很好的体现美国 DOHaD 协会自 2016 年成立以来每年召开全国会议就是一个例子。汇集了具有不同背景的调查人员，否则他们可能不会互动，包括那些研究领域包括发育生物学、生命历程流行病学、营养学、环境毒理学、这些人遍布美国各地的机构，从大学到工业界。向政府机构（NIH、EPA、NIEHS）分享知识和最新进展环境毒物、营养素、药剂、病原体、肠道微生物群、压力和新兴疾病影响胎儿和新生儿发育的因素，从而影响他们的健康和疾病此外，演讲还深入探讨了这些因素如何可能对生命周期造成有害影响。后代，即跨代效应美国 DOHaD 协会年度的主要目标。第二次会议的目的是促进多学科互动并促进在这些不同主题上的合作。目标是为学员（研究生、博士后研究员和初级教师）提供机会与世界知名专家互动，促进未来科学家的发展和职业机会第三个目标是继续促进性别的多样性、包容性和平等代表性。少数群体作为发言人和会议领导人的代表性不足，特别是妇女和少数群体。在过去五次会议中，发言者和主持人的比例分别超过 50% 和 >20%。会议取得了巨大成功，特别是 2021 年混合（现场和虚拟）会议尽管新冠病毒大流行仍在继续，但这些成功为持续且永久的年度活动提供了动力。第六届、第七届和第八届年会将再次以混合形式在大学举行。明尼苏达州（明尼阿波利斯，2022 年）、慈善儿童医院（堪萨斯城，2023 年）和里佐中心（教堂教堂） Hill，2024），2022 年会议的主题将是“环境暴露：评估”。与 2021 年会议类似，该计划将包括“方法、机制和健康成果”。专门为所有初级学员提供职业发展和资助写作的一天。 2023 年和 2024 年的主题将涵盖孕产妇微生物群和儿童发育、外泌体等主题生物标志物携带者，母亲补充叶酸、胆碱和 DHA 对后代健康结果的影响与表观基因组变化相关，以及相关长期健康结果的流行病学分析简而言之，美国 DOHaD 协会的优势在于它。它所代表的研究和这些领域的研究人员的多样性。