Pre-doctoral Training Program in Integrative Vascular Biology

综合血管生物学博士前培训项目

• 批准号: 10494864
• 负责人: Christopher P. Mack
• 金额: $ 48.52万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-04-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10494864
• 关键词: Biology; Blood Vessels; Training Programs; pre-doctoral

Project Summary - The complexity of cardiovascular disease has hindered our understanding of its deveopment and progression. To uncover the mechanisms by which genetic variation and environmental factors influence cardiovascular development and disease, the next generation of scientists will need to be trained to use a variety of approaches, technologies and model systems. In response to this demand, the Integrative Vascular Biology (IVB) Pre-doctoral Training Program was established at UNC in 2002 to promote a collaborative interdisciplinary training environment for pre-doctoral students in the cardiovascular field. The IVB Program combines the breadth and depth of the cardiovascular research faculty with other research strengths at UNC in genetic model systems, state-of-the-art cell biology and imaging, high throughput genomic and proteomic analyses, and computational biology. The overall goal of the IVB Program is to provide Trainees with the interdisciplinary and collaborative skills necessary to extend their thesis work into new, innovative, and productive directions. Specific Aim 1 is to connect Trainees in broad areas of cardiovascular research by requiring them to collaborate with secondary mentors outside of their field. This training mechanism was specifically designed to “connect” graduate students in broad areas of cardiovascular biology and cardiovascular health research. The program teaches students to apply molecular, cellular, genetic, and computational approaches to pathological and physiological questions in cell, organ, and whole animal systems; to merge hypothesis- and discovery-based research; and to develop high-throughput approaches for use in complex models. Specific Aim 2 is to provide Trainees with a broad understanding of cardiovascular development and disease. This will be achieved through advanced paper-based cardiovascular courses, cardiovascular seminars by leaders in the field, and through bi-weekly student-led discussion groups. Specific Aim 3 is to enhance the skills necessary for effective collaboration and career advancement. Trainees will improve their communication skills by presenting their work at formal and informal IVB events and students will attend IVB Workshops on grant writing, career development, and scientific rigor and responsibility. The IVB Program is administered by UNC McAllister Heart Institute and is directed by Dr. Christopher Mack a respected vascular biologist who has been heavily involved in graduate student training at multiple levels. He is assisted by Associate Director, Vicki Bautch, and former IVB director Nobuyo Maeda. The major strength of the Program is the breadth and diversity of the 42 primary training faculty who are committed to graduate student training, extremely well-funded, and using cutting edge approaches to answer a wide-variety of cardiovascular questions. When combined with a well-developed academic program in Cardiovascular Science (also directed by Dr. Mack) and a large pool of well-qualified applicants, the UNC Integrative Vascular Biology Program offers an outstanding environment for multidisciplinary training of pre-doctoral students.

项目摘要 - 心血管疾病的复杂性阻碍了我们对其的理解 揭示遗传变异和环境的机制。 影响心血管发育和疾病的因素，下一代科学家需要 为了满足这一需求，培训人员使用各种方法、技术和模型系统。 综合血管生物学 (IVB) 博士前培训项目于 2002 年在北卡罗来纳大学设立，旨在促进 IVB 为心血管领域的博士前学生提供协作的跨学科培训环境。 该计划将心血管研究人员的广度和深度与其他研究优势相结合 北卡罗来纳大学的遗传模型系统、最先进的细胞生物学和成像、高通量基因组和 IVB 计划的总体目标是为学员提供蛋白质组分析和计算生物学。 具有将论文工作扩展到新的、 具体目标 1 是在广泛的领域将学员联系起来。 心血管研究要求他们与自己领域之外的二级导师合作。 培训机制是专门为“连接”心血管广泛领域的研究生而设计的 该课程教授学生应用分子、细胞、 细胞、器官和整体病理和生理问题的遗传和计算方法 动物系统；融合基于假​​设和发现的研究；并开发高通量 具体目标 2 是让学员广泛了解复杂模型中使用的方法。 这将通过先进的纸质心血管来实现。 课程、该领域领导者举办的心血管研讨会以及每两周一次的学生主导的讨论小组。 具体目标 3 是提高学员有效协作和职业发展所需的技能。 将通过在正式和非正式的 IVB 活动和学生中展示他们的作品来提高他们的沟通技巧 将参加有关拨款写作、职业发展、科学研究和责任的 IVB 研讨会。 该计划由北卡罗来纳大学麦卡利斯特心脏研究所管理，并由 Christopher Mack 博士指导。 他是一位受人尊敬的血管生物学家，积极参与多个级别的研究生培训。 由副主任 Vicki Bautch 和前 IVB 主任 Nobuyo Maeda 协助。 该计划涵盖了 42 名初级培训教师的广度和多样性，他们致力于毕业 学生培训，资金极其充足，并使用尖端方法来回答各种各样的问题 心血管问题与完善的心血管科学学术课程相结合。 （也由麦克博士指导）和大量合格的申请者，北卡罗来纳大学综合血管生物学 该项目为博士前学生的多学科培训提供了良好的环境。