Core A: Administrative Core

核心A：行政核心

• 批准号: 10495879
• 负责人: ELECTRA D. PASKETT
• 金额: $ 14.94万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-04-11 至 2024-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10495879
• 关键词: Core; Administrative

The overall goal of the Administrative Core (AC) is to provide a structure to facilitate effective interactions toward accomplishment of the aims of this Program Project. To accomplish this goal, the AC will be structured into a Steering Committee and a Project Management Team. These groups will work together to accomplish the following specific aims: 1) Provide research direction by setting the research agenda focused on addressing cervical cancer disparities in Appalachia and promoting transdisciplinary research; 2) Ensure operational efficiency for all components of the Program by providing centralized grant administration, information dissemination, budget data processing, and seamless exchange of information and services; and 3) Promote integration of the Projects and Cores (Survey and Data Collection, Intervention and Consortium, and Biostatistics and Evaluation) to promote interaction among the four Universities, the investigators, the Appalachian communities, the participating community clinics/health systems; and relevant external entities. The proposed AC builds upon the successful experience of the structure of the Appalachian Community Cancer Network (P30 CA016058), in which the Multiple Principal Investigators (MPIs) worked together for over 10 years. The proposed structure will be led by a Headquarters unit located at The Ohio State University and be directed by MPIs, Drs. Paskett, Anderson, Dignan and Kennedy. The members of this team are well acquainted and have a track record of conducting research projects together, as well as each has substantial experience with conducting community based research in Appalachia. We have designed an organizational and administrative structure that defines and preserves clear responsibilities and facilitates interactive dependence among projects and cores. The MPIs will be responsible for day-to-day oversight of the important milestones, and integration among all Program components. The AC will also oversee the operation of the Steering Committee, an External Scientific Advisory Committee, comprised of four scientists from outside institutions, and will also work with the Intervention and Consortium Core to facilitate input from and meetings with members of the Community Advisory Board and the Clinical Partners, assuring Community-Based Participatory Research in all the aspects of the Program, and be responsible for regular meetings of the Data and Safety Monitoring Board, in conjunction with the Biostatistics and Evaluation Core. The Program also has two consultants – Drs. Mack Ruffin and Jaimie Ostroff – to advise on clinical issues and Implementation Science, respectively. Lastly, the AC will ensure that all components of the Program work seamlessly together to accomplish the Overall and specific project goals of the Program Project and that the two conceptual models which underlie the research – the Multi-Level Model for Addressing Health Disparities (for intervention and assessment) and the Proctor Implementation Framework (for implementation and evaluation of the interventions) are fully embraced and integrated.

行政核心 (AC) 的总体目标是提供一个结构，以促进有效互动，以实现该计划项目的目标。为了实现这一目标，AC 将分为指导委员会和项目管理团队。各小组将共同努力实现以下具体目标： 1) 通过制定专注于解决阿巴拉契亚宫颈癌差异和促进跨学科研究的研究议程来提供研究方向； 2) 通过提供集中拨款管理来确保该计划所有组成部分的运作效率； ， 信息传播、预算数据处理以及信息和服务的无缝交换；3) 促进项目和核心（调查和数据收集、干预和联盟以及生物统计和评估）的整合，以促进四所大学、研究人员、阿巴拉契亚社区、参与的社区诊所/卫生系统和相关外部实体；拟议的 AC 以阿巴拉契亚社区癌症网络结构的成功经验为基础（P30）。 CA016058），其中多个首席研究员 (MPI) 合作了 10 多年，拟议的结构将由位于俄亥俄州立大学的总部单位领导，并由 MPI、Paskett、Anderson、Dignan 和 Kennedy 博士领导。该团队的成员非常熟悉，并且拥有共同开展研究项目的记录，并且每个人都拥有在阿巴拉契亚开展社区研究的丰富经验。定义和保留明确职责并促进项目和核心之间相互依赖的管理结构 MPI 将负责重要里程碑的日常监督，并且审计委员会还将监督所有计划组成部分的运作。指导委员会是一个外部科学咨询委员会，由来自外部机构的四名科学家组成，还将与干预和联盟核心合作，促进社区咨询委员会和临床合作伙伴成员的意见和会议，确保基于社区的该计划的各个方面进行参与性研究，并与生物统计和评估核心一起负责数据和安全监测委员会的定期会议。该计划还有两名顾问——Mack Ruffin 博士和 Jaimie Ostroff 博士——提供建议。最后，AC 将确保该计划的所有组成部分无缝地协同工作，以实现该计划项目的总体和具体项目目标以及该研究的两个概念模型 - 多学科模型。等级解决健康差异模型（用于干预和评估）和 Proctor 实施框架（用于干预措施的实施和评估）得到充分接受和整合。