Evaluating Sleep Deficiency in Aging Populations
评估老龄化人群的睡眠不足
基本信息
- 批准号:10493398
- 负责人:
- 金额:$ 23.86万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2021
- 资助国家:美国
- 起止时间:2021-09-30 至 2026-05-31
- 项目状态:未结题
- 来源:
- 关键词:AcademyAddressAdverse effectsAgeAgingAmericanAssessment toolAwardAwarenessCapsicumClinicalDataDetectionDevelopmentDevice or Instrument DevelopmentDiagnosisDrowsinessElderlyElectroencephalographyEnvironmentEtiologyFoundationsFutureGeriatricsGillsGoalsGrantHealthHome environmentHypersomniasImpaired cognitionImpairmentInstitutionalizationInternationalInterventionInterviewK-Series Research Career ProgramsLaboratoriesMeasuresMedicineMentorsMethodsMinority GroupsMorbidity - disease rateNatureNocturiaNormal RangeOutcomePatient Self-ReportPerceptionPersonsPhasePhysical PerformancePhysiciansPolysomnographyPopulationPublicationsQualitative MethodsQuestionnairesReference StandardsReportingResearchResearch DesignResearch MethodologyResearch PersonnelResearch Project GrantsResearch TrainingResourcesScheduleSleepSleep Apnea SyndromesSleep DeprivationSleep DisordersSleep disturbancesSleeplessnessSocietiesSpecialistSymptomsTestingTrainingTraining ProgramsUnited States National Institutes of HealthUniversitiesWorkactigraphyadverse outcomebasecareercareer developmentcircadian biologyclinical epidemiologycohortepidemiology studyexpectationexperienceflexibilityfunctional declinefunctional disabilityimprovedinstrumentleadership developmentmedical schoolsmortalitynovelpilot testpoor sleeppreventprogramsresearch and developmentresponsescreeningsleep healthsleep qualitystandard measuresuccesstherapeutic targettooltraining opportunityvigilance
项目摘要
PROJECT SUMMARY/ABSTRACT
Candidate: My career goal is to become an independent clinician-investigator focused on improving sleep-
wake disturbances and preventing their adverse outcomes in older persons. My clinical training as a Geriatrics
and Sleep Medicine physician and research training in Geriatric Clinical Epidemiology form the foundation on
which I will build to reach this goal. My track record of success is evidenced by the publication of high-impact
original reports and the receipt of 3 grants. I have distinguished myself as a national leader and received
awards for my research from the Sleep Research Society, the American Academy of Sleep Medicine (AASM),
and the American Geriatrics Society (AGS), including the AGS New Investigator Award and a career
development award from the AASM Foundation.
Mentors and Environment: I have an outstanding team of mentors and advisors, including my primary
mentor, Dr. Thomas Gill (Geriatrics), an internationally recognized thought leader in aging research, and co-
mentor Dr. Klar Yaggi (Sleep Medicine), an expert in conducting epidemiologic studies aimed at understanding
the health outcomes of sleep disorders. I also have a team of advisors, selected based on their expertise in
aging, sleep, qualitative and mixed-methods research, circadian biology and analysis, and instrument
development. I have outlined a rigorous program of training that draws upon the wealth of resources across
Yale University, including the Program on Aging/Claude D. Pepper Older Americans Independence Center, as
well as national training opportunities in mixed methods research and leadership development. These
resources, and the support of the Sections of Geriatrics and Sleep Medicine at the Yale School of Medicine,
provide an ideal environment for my career development and execution of the proposed research.
Mentored Research Project: Sleep-wake disturbances are associated with important adverse outcomes in
older persons, including cognitive and functional decline. Our prior work has demonstrated that these
disturbances are under-diagnosed in older persons, which may be due to the poor sensitivity of existing sleep
questionnaires, the frequent co-occurrence of multiple sleep-wake disturbances, and the burdensome nature of
objective sleep testing. We propose to develop and test age-appropriate, comprehensive subjective and
objective sleep assessment tools to facilitate identification of older persons with sleep-wake disturbances.
To accomplish this, we will assess sleep-wake disturbances using a broader construct termed, “sleep
deficiency”, which is a condition causing functional impairment as a result of a deficit in sleep quality, sleep
duration, and/or sleep that is out-of-sync with the body's natural clock (i.e., non-circadian sleep). The overall
objective is to develop and pilot test tools to identify sleep deficiency in older persons. Future work will validate
these tools, which can be used to target interventions to improve sleep health and prevent adverse outcomes.
项目概要/摘要
候选人:我的职业目标是成为一名专注于改善睡眠的独立临床医生-研究员-
我作为老年病学的临床培训。
睡眠医学医师和老年临床流行病学研究培训奠定了基础
我将通过出版具有高影响力的书来证明我的成功记录。
原始报告并获得 3 项资助 我作为国家领导人表现出色并获得了资助。
睡眠研究协会、美国睡眠医学会 (AASM) 授予我的研究奖项,
和美国老年病学会 (AGS),包括 AGS 新研究者奖和职业生涯
AASM 基金会颁发的发展奖。
导师和环境:我有一支优秀的导师和顾问团队,包括我的主要导师和顾问
导师托马斯·吉尔 (Thomas Gill) 博士(老年病学)是国际公认的老龄化研究思想领袖,
导师 Klar Yaggi 博士(睡眠医学),一位进行流行病学研究的专家,旨在了解
我还有一个顾问团队,他们是根据他们在睡眠障碍方面的专业知识而挑选的。
衰老、睡眠、定性和混合方法研究、昼夜节律生物学和分析以及仪器
我概述了一个严格的培训计划,该计划利用了丰富的资源。
耶鲁大学,包括老龄化项目/Claude D. Pepper 美国老年人独立中心,
以及混合方法研究和领导力发展方面的国家培训机会。
资源以及耶鲁大学医学院老年病学和睡眠医学科的支持,
为我的职业发展和拟议研究的执行提供理想的环境。
指导研究项目:睡眠-觉醒障碍与重要的不良后果相关
老年人,包括认知和功能下降,我们之前的工作已经证明这些。
老年人的睡眠障碍诊断不足,这可能是由于现有睡眠的敏感性较差
问卷调查、多种睡眠-觉醒障碍的频繁同时发生以及睡眠-觉醒障碍的繁重本质
我们建议开发和测试适合年龄的、全面的主观和睡眠测试。
客观的睡眠评估工具,有助于识别患有睡眠-觉醒障碍的老年人。
为了实现这一目标,我们将使用更广泛的概念来评估睡眠-觉醒障碍,称为“睡眠”。
睡眠不足”,这是一种由于睡眠质量、睡眠不足而导致功能障碍的病症
持续时间和/或与人体自然时钟不同步的睡眠(即非昼夜节律睡眠)。
目标是开发和试点测试工具来识别老年人的睡眠不足,未来的工作将进行验证。
这些工具可用于有针对性的干预措施,以改善睡眠健康并预防不良后果。
项目成果
期刊论文数量(0)
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{{ truncateString('BRIENNE MINER', 18)}}的其他基金
Evaluating Sleep Deficiency in Aging Populations
评估老龄化人群的睡眠不足
- 批准号:
10337745 - 财政年份:2021
- 资助金额:
$ 23.86万 - 项目类别:
Evaluating Sleep Deficiency in Aging Populations
评估老龄化人群的睡眠不足
- 批准号:
10646363 - 财政年份:2021
- 资助金额:
$ 23.86万 - 项目类别:
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