REPRODUCTIVE BIOLOGY SYMPOSIUM

生殖生物学研讨会

• 批准号: 2204840
• 负责人: JANICE M BAHR
• 金额: $ 1万
• 依托单位: UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN
• 依托单位国家: 美国
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-07-01 至 1995-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2204840
• 关键词: epididymis; meeting /conference /symposium; testis; travel

Funds are requested to provide partial support for a Symposium entitled, "Testicular and Epididymal Function", and two State of the Art presentations to be presented at the 27th Annual Meeting of the Society for the Study of Reproduction (SSR). Travel awards for trainees (non- NRSA recipients) are also requested. The SSR meeting will be held at the University of Michigan, Ann Arbor, MI, July 24-27, 1994. The topic of the symposium was selected because of the interest of the membership, its importance in reproductive biology and the absence of a symposium in this area for 15 years. The three invited speakers are internationally recognized scientists. Dr. M. Griswold will address the role and regulation of Sertoli cells in spermatogenesis. Specifically he will focus on the obligatory relationship of Sertoli and germ cells in the production of sperm. Dr. A. Payne will discuss the regulation of the expression of steroidogenic enzymes in Leydig cells. She will present studies in which she investigated the hormonal regulation, tissue-specific expression and chromosomal location of these steroidogenic enzymes in the mouse. Dr. B. Robaire will discuss the epididymal epithelium and how this dynamically changing tissue is regulated. Dr. Robaire will focus on the regulation of 5alpha-reductase, epithelial-cadherin, SGP-2, and GST. The two State of the Art lectures will focus on novel techniques applicable to reproductive studies. Dr. S. Camper will explain the use of transgenic and embryonic stem cell technology to study gene expression, cell-cell interactions and gene function. She will review and discuss the use of transgenic mice to overexpress or ectopically express genes generating animal models of hyperplasia, tumorigenesis, and other disease states to test efficacy of gene therapy, and to study cell-cell interactions and lineage relationships of cell during development. Dr. J. Robinson will describe the use of in vivo microdialysis to deliver substances (e.g. receptor agonist, antagonists) to a specific site within a tissue and to sample substances in limited samples of fluid. The techniques can be used for studies in gonads, uterus, pituitary gland, brain, blood, etc. in the conscious freely moving animal. Funds are also requested for travel awards to trainees because the SSR meeting is a very friendly meeting for trainees, allowing them to meet senior scientists and to present their research. The majority of the papers presented are given by trainees. Support of trainees has allowed many more trainees to attend SSR who otherwise may not be able to attend.

要求资金为题材的专题讨论会提供部分支持 “睾丸和附子函数”和两个最新状态 演讲将在协会第27届年会上介绍 用于繁殖研究（SSR）。 学员的旅行奖（非 - 还请求NRSA收件人）。 SSR会议将在 密歇根大学，密歇根州安阿伯市，1994年7月24日至27日。 因座位的利益而选择了研讨会的主题 会员资格，其在生殖生物学中的重要性以及缺乏 该地区的研讨会持续了15年。 三个邀请的演讲者是 国际公认的科学家。 M. Griswold博士将解决 Sertoli细胞在精子发生中的作用和调节。 具体来说 他将专注于Sertoli和生殖细胞的强制性关系 在精子的生产中。 A. Payne博士将讨论 leydig细胞中类固醇生成酶的表达。 她会的 她研究了荷尔蒙调节的研究， 这些组织特异性表达和染色体位置 小鼠中的类固醇生成酶。 B. Robaire博士将讨论 附子上皮以及这种动态变化的组织是如何 受监管。 Robaire博士将重点介绍5Alpha-reductase的调节， 上皮 - 钙粘蛋白，SGP-2和GST。 两个最新讲座的状态 将专注于适用于生殖研究的新技术。 博士 S. Camper将解释转基因和胚胎干细胞的使用 研究基因表达，细胞 - 细胞相互作用和基因的技术 功能。 她将审查并讨论转基因小鼠的使用 过表达或异位表达产生动物模型的基因 增生，肿瘤发生和其他疾病状态以检验 基因疗法，研究细胞 - 细胞相互作用和谱系 开发过程中细胞的关系。 J. Robinson博士将描述 使用体内微透析递送物质（例如受体 激动剂，拮抗剂）到组织内的特定位点，然后样品 有限的流体样品中的物质。 这些技术可用于 在性腺，子宫，垂体，大脑，血液等中进行研究 有意识自由移动的动物。 还要求旅行资金 颁发学员的奖项，因为SSR会议是一次非常友好的会议 学员，允许他们见面高级科学家，并介绍他们的 研究。 发表的大多数论文都是由学员发表的。 对学员的支持使更多的学员参加了SSR 否则可能无法参加。