Core A: Administrative Core

核心A：行政核心

• 批准号: 10468306
• 负责人: Neil W. Kowall
• 金额: $ 38.93万
• 依托单位: BOSTON UNIVERSITY MEDICAL CAMPUS
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-15 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10468306
• 关键词: Accountability; Administrative Personnel; Advisory Committees; Alzheimer' s Disease; Alzheimer' s disease related dementia; Area; Biological; Boston; Budgets; Clinical; Collaborations; Communities; Community Actions; Data Set; Development; Educational workshop; Ensure; Feedback; Fostering; Framingham Heart Study; Goals; Heart; Heterogeneity; Individual; Industry; Infrastructure; Interactive Communication; International; Knowledge; Late Effects; Leadership; Medical center; Mentors; Mission; Molecular Profiling; Monitor; Nature; Performance; Policies; Prevention; Process; Process Assessment; Program Reviews; Recommendation; Reporting; Research; Research Ethics; Research Personnel; Resources; Review Committee; Role; Scientist; Self Assessment; Site; Source; Specimen; Strategic vision; Structure; Technology; Thinking; Time; Training; United States National Institutes of Health; Universities; Women' s Health; Work; black women; career development; cohort; community organizations; digital; disease heterogeneity; head impact; high risk; high standard; human subject; improved; innovation; medical schools; next generation; novel; prevent; programs; public-private partnership; symposium

Since its inception in 1996, the Boston University (BU) Alzheimer Disease (AD) Research Center (ADRC) has had a singular mission to facilitate leading-edge research on Alzheimer's disease (AD) and AD related dementias (ADRD). The function of the Administrative Core (AC) is to ensure that administrative processes are in place to support this mission. The Core manages and coordinates internal interactions between the ADRC director and core leaders, interactions between the BU ADRC and investigators at BU and elsewhere, BU administration, staff at NIA, and local and national community organizations. The AC integrates, coordinates, directs and plans all BU ADRC activities and ensures compliance with all human subjects, scientific integrity, and financial policy requirements of NIH. This includes providing an effective structure to support our scientific efforts focused on studying AD/ADRD disease heterogeneity, ensuring the availability of our diverse cohorts, and supporting and implementing the themes and goals of the National Alzheimer's Plan Project Act (NAPA). The progress of the ADRC as a whole and its individual core component will be monitored to ensure accountability to NAPA and NIA milestones and goals. The AC fosters innovative AD/ADRD research by providing visionary leadership and by facilitating cross-core interactions and coordinating the provision of resources to support qualified investigators at BU and other local, national, and international research programs. The AC facilitates partnerships with the local, regional, national and international AD/ADRD research community to support high-impact AD/ADRD research. The AC will ensure that all mandated data sets are submitted to NACC in an accurate and timely manner and that biological specimens are submitted to the NCRAD. The AC ensures that we support and inform the communities we serve regarding the benefits of the BU ADRC and AD/ADRD research and to solicit feedback and advice from them. The AC is under the leadership of BU ADRC Director Dr. Neil Kowall who reports directly to the Dean of BU School of Medicine. In his role as BU ADRC Director he is supported by an Executive Committee comprised of BU ADRC core leaders and other senior thought leaders at BU. Other administrative committees include an External Advisory Committee, Internal Advisory Committee, and Community Action Council. In collaboration with the BU ADRC Director, these committees are responsible for coordinating, planning, overseeing, and evaluating all BU ADRC activities and ensuring the optimal utilization of BU ADRC resources. The AC administers the developmental project program to support meritorious projects focused on basic or clinical AD/ADRD research. A Developmental Project Review Panel will be commissioned review, select, and monitor these projects. Ongoing, interactive communication and input will be solicited from multiple sources, including our institutional research community, external AD/ADRD experts, and NIA, to strengthen and improve our Center's performance.

自 1996 年成立以来，波士顿大学 (BU) 阿尔茨海默病 (AD) 研究中心 (ADRC) 已 肩负着一项独特的使命，即促进阿尔茨海默病 (AD) 及 AD 相关疾病的前沿研究 痴呆症（ADRD）。行政核心 (AC) 的职能是确保行政流程 到位以支持这一使命。核心管理和协调 ADRC 之间的内部互动 主任和核心领导者、BU ADRC 与 BU 及其他地方的调查人员之间的互动 行政部门、NIA 工作人员以及当地和国家社区组织。 AC 集成、协调、 指导和计划所有 BU ADRC 活动，并确保遵守所有人类受试者、科学完整性、 以及 NIH 的财务政策要求。这包括提供有效的结构来支持我们的科学 工作重点是研究 AD/ADRD 疾病异质性，确保我们多样化队列的可用性， 支持和实施国家阿尔茨海默病计划项目法案 (NAPA) 的主题和目标。 ADRC 的整体进展及其各个核心部分将受到监测，以确保 对 NAPA 和 NIA 里程碑和目标的责任。 AC 通过以下方式促进创新 AD/ADRD 研究 提供有远见的领导力，促进跨核心互动并协调提供 支持波士顿大学和其他地方、国家和国际研究合格研究人员的资源 程序。 AC 促进与地方、区域、国家和国际 AD/ADRD 的伙伴关系 研究界支持高影响力的 AD/ADRD 研究。审计委员会将确保所有规定的数据 准确及时地将样本集提交给 NACC，并将生物样本提交给 NCRAD。审计委员会确保我们支持并告知我们所服务的社区有关以下方面的好处 BU ADRC 和 AD/ADRD 研究，并征求他们的反馈和建议。空调位于 BU ADRC 主任 Neil Kowall 博士的领导，直接向 BU 医学院院长汇报。在 作为 BU ADRC 主任，他得到由 BU ADRC 核心组成的执行委员会的支持 BU 的领导者和其他高级思想领袖。其他管理委员会包括外部顾问 委员会、内部咨询委员会和社区行动委员会。与 BU ADRC 合作 主任，这些委员会负责协调、规划、监督和评估所有 BU ADRC 活动并确保 BU ADRC 资源的最佳利用。 AC 负责管理发展 项目计划，支持专注于基础或临床 AD/ADRD 研究的优秀项目。一个 发展项目审查小组将受委托审查、选择和监督这些项目。 将从多个来源征求持续的互动沟通和意见，包括我们的机构 研究界、外部 AD/ADRD 专家和 NIA，以加强和改进我们中心的 表现。