PHARMACEUTICAL RESEARCH CENTER

药物研究中心

• 批准号: 3058700
• 负责人: FREDERICK S HUMPHRIES
• 金额: $ 61.75万
• 依托单位: FLORIDA AGRICULTURAL AND MECHANICAL UNIV
• 依托单位国家: 美国
• 财政年份: 1985
• 资助国家: 美国
• 起止时间: 1985-09-30 至 1995-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3058700
• 关键词: minority institution research support; pharmacy administration

Long term objective: to establish a high level of competitiveness in pharmaceutical research. Specific aims: enhance faculty and student understanding- of, and capability in, proposal preparation; strengthen library holdings to support PhD tracks and research in pharmacology/ toxicology, medicinal chemistry and environmental toxicology; increase animal holding space; provide foundational support for newly hired faculty train minority recipients of PhD, PharmD, DVM, and MD degrees in pharma- ceutical research; develop new potent and safe drugs; and to investigate ethnopharmacological phenomena in certain disease states. Methods. The administrative infrastructure will identify funding opportunities, provide statistical, editorial, graphics, and word processing support, and both internal and external review for proposals. A proposal preparation and grant administration course and a state-of-the-art research seminar series will be established. Basic and supplementary text will be secured to enhance library research. CD-ROM MEDLINE, DIALOG, and National Library of Medicine on-line search capabilities will be provided. State-of-the-art cages will house mice and rats. New research oriented basic science and clinical pharmacy faculty protocols will be evaluated for the merit of requests for foundational general purpose equipment. Minority health science doctoral degree recipients will receive experience and guidance in the conduct of pharmaceutical research. New drugs will be synthesized and screened to determine activity. The bases for ethnic differences in the pharmacokinetics and pharmacodynamics of analgesics, drugs used to treat cancer, and hypertensive agents in elderly African-American and Hispanics will be studied. Restriction fragment length polymorphism techniques will be used to elucidate the molecular basis for ethnic differences in drug response.

长期目标：建立高水平的竞争力 制药研究。具体目的：增强教师和学生 对提案准备的理解和能力；加强 图书馆持有的博士轨道和药理学研究/ 毒理学，药物化学和环境毒理学；增加 动物持有空间；为新雇用的教师提供基本支持 培训Pharma-thema-trak，PharmD，DVM和MD学位的少数民族接受者 校园研究；开发新的有效和安全的药物；并进行调查 某些疾病状态中的民族药物现象。方法。这 行政基础设施将确定资金机会，提供 统计，社论，图形和文字处理支持，以及 内部和外部审查提案。提案准备和 赠款管理课程和最先进的研究研讨会系列 将建立。基本和补充文本将被确保 增强图书馆研究。 CD-ROM MEDLINE，对话和国家图书馆 将提供在线搜索功能。最先进的 笼子将容纳老鼠和老鼠。新研究的基础科学和 将评估临床药房教师方案的优点 基础通用设备的要求。少数民族健康 科学博士学位获得者将获得经验和指导 药物研究的行为。新药将合成，并 筛选以确定活动。种族差异的基础 镇痛药的药代动力学和药效学，用于治疗的药物 非裔美国人和西班牙裔老年人的癌症和高血压药 将被研究。限制片段长度多态性技术将 用于阐明药物种族差异的分子基础 回复。