MATCHES: Making Telehealth Delivery of Cancer Care at Home Effective and Safe

匹配：使远程医疗在家中提供有效且安全的癌症护理

基本信息

批准号：
10454670
负责人：
MICHAEL J MORRIS
金额：
$ 123.9万
依托单位：
SLOAN-KETTERING INST CAN RESEARCH
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-08-01 至 2027-07-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10454670
关键词：
Address Adoption Ambulatory Care Facilities Biological Models COVID-19 pandemic Cancer Patient Caring Chronic Clinic Clinical Medicine Communication Computerized Medical Record Custom Data Data Analytics Data Science Devices Diagnosis Dimensions Discipline Diverse Workforce Dose Ecosystem Effectiveness Electronic Health Record Ensure Feedback Future Goals Growth Health Services Heart failure Home Individual Informatics Institute of Medicine (U.S.)Intervention Intramuscular Knowledge Laboratories Link Machine Learning Malignant Neoplasms Medicine Metadata Methods Modeling Monitor New Jersey New York Oncology Oral Outcome Outcome Measure Outpatients Palliative Care Patients Pattern Persons Physicians Prostate Cancer therapy Quality of Care Randomized Research Research Design Research Methodology Research Personnel Resources Risk Rural Safety Science Site System Techniques Testing Time Training Visit Woman Work analytical method asynchronous communication base behavioral health cancer care cancer therapy care delivery clinical practice complex data data streams design digital evidence base experience health care quality health communication health equity implementation science individual patient innovation insight investigator training mHealth machine learning method malignant breast neoplasm men multidisciplinary novel pandemic disease patient portal personalized care pilot trial pragmatic trial precision oncology prospective rational design skills subcutaneous survivorship telehealth tool trial comparing trial design virtual visit

项目摘要

Project Summary/Abstract The MATCHES (Making Telehealth Delivery of Cancer Care at Home Effective and Safe) Telehealth Research Center aims to build the evidence base necessary to establish best practices for telehealth-enabled cancer care. The overarching goal of the Center is to create a research hub that generates evidence, trains investigators, and develops the research methods required to ignite the field of precision cancer care delivery. Prior work demonstrates that oncology-focused telehealth can achieve favorable outcomes, but large-scale trials have been limited to specific contexts like palliative care or survivorship. Adoption has been constrained by restricted reimbursement. The MATCHES Center will help remediate this evidence gap by executing prospective trials, conducting observational analyses, and training transdisciplinary researchers. Our research theme focuses on the integration of multi-layered data from telehealth platforms, patient portals, mobile tracking devices, and the electronic medical record to develop analytic methods that support personalized care. We aim to develop a new paradigm in oncology—precision delivery—with the ultimate goal of matching individual patients with the most beneficial combination of clinic-based or telehealth-supported home-setting care at the appropriate time—all based on the totality of dynamically available data. We will accomplish this goal by applying data science methods—including nimble trial designs and machine learning—that have had limited application to telehealth to date. By establishing a research hub that nurtures investigators across disciplines and provides training, tools, data, analytic methods, and venues for sharing knowledge and building partnerships, we expect to accelerate progress in the science of care delivery. Our specific aims are 1) to conduct impactful pragmatic trials of telehealth in oncology, 2) to analyze a large existing cache of multidimensional observational data characterizing telehealth utilization and outcomes, 3) to train investigators and equip them with the skills necessary to innovate within an evidence-based framework, and 4) to integrate telehealth with other data streams and create and apply analytic methods to transform the field of precision care delivery. An Administrative Core will coordinate activities and engage feedback from internal and external stakeholders—including patients and the oncology workforce. Our Clinical Practice Network serves as an innovation laboratory and comprises 7 outpatient clinics in NY and NJ with a shared informatics ecosystem including telehealth capacity, digital monitoring, and a highly trafficked patient portal. This will enable us to launch and execute a large pragmatic trial comparing in-person care to telehealth, with resources designed to support home-based care using a cluster-randomized design. The Research & Methods Core will support the Center by applying data science methods to extract and synthesize insights from telehealth and other data streams to develop methods relevant to advancing precision cancer care delivery and the goals of equity, efficacy, and efficiency to create an optimal experience for people being treated for cancer.

项目概要/摘要比赛（使远程医疗在家中提供有效且安全的癌症护理）远程医疗研究该中心旨在建立必要的证据基础，以建立远程医疗癌症的最佳实践该中心的总体目标是创建一个产生证据、培训的研究中心。研究人员，并开发点燃精准癌症护理领域所需的研究方法。先前的工作表明，以肿瘤学为重点的远程医疗可以取得良好的结果，但大规模试验仅限于姑息治疗或幸存者等特定情况。 MATCHES 中心将通过执行有限的报销来帮助弥补这一证据差距。前瞻性试验、进行观察分析并培训跨学科研究人员。主题侧重于来自远程医疗平台、患者门户、移动设备的多层数据的集成跟踪设备和电子病历，以开发支持个性化的分析方法我们的目标是开发肿瘤学的新范式——精准治疗——最终目标是匹配。个体患者拥有基于诊所或远程医疗支持的家庭环境的最有益组合在适当的时间进行护理——所有这些都基于动态可用数据的整体。通过应用数据科学方法（包括灵活的试验设计和机器学习）来实现目标迄今为止，通过建立一个培养研究人员的研究中心，远程医疗的应用有限。学科并提供培训、工具、数据、分析方法以及共享知识和构建的场所合作伙伴关系，我们期望加速医疗服务科学的进步，我们的具体目标是 1) 对肿瘤学远程医疗进行有效的务实试验，2) 分析大量现有的信息表征远程医疗利用和结果的多维观察数据，3) 培训调查人员并为他们配备在循证框架内进行创新所需的技能，以及 4) 整合远程医疗与其他数据流，并创建和应用分析方法来改变精确领域行政核心将协调活动并吸收内部和外部的反馈。利益相关者——包括患者和肿瘤学工作人员，我们的临床实践网络作为一个。创新实验室，由纽约州和新泽西州的 7 个门诊诊所组成，具有共享的信息学生态系统包括远程医疗能力、数字监控和高流量的患者门户，这将使我们能够启动并执行一项大型务实试验，比较现场护理与远程医疗，并利用旨在使用整群随机设计支持家庭护理研究与方法核心将支持中心应用数据科学方法从远程医疗和其他数据中提取和综合见解致力于开发与推进精准癌症护理服务和公平目标相关的方法，功效和效率，为癌症治疗患者创造最佳体验。