Molecular Medicine Training Program at Cleveland Clinic/Case Western Reserve University

克利夫兰诊所/凯斯西储大学分子医学培训项目

• 批准号: 10426323
• 负责人: Jonathan D Smith
• 金额: $ 31.22万
• 依托单位: CLEVELAND CLINIC LERNER COM-CWRU
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10426323
• 关键词: Clinic; Molecular Medicine; Training Programs; Universities

The Molecular Medicine Training Program of the Case Western Reserve University School of Medicine is specifically designed to introduce medical knowledge into graduate training and foster translational research relevant to human disease. It is one of the very few stand-alone Molecular Medicine PhD programs in the United States. It takes advantage of four factors to create an environment particularly suited to this purpose. First, this Program is located in the Lerner Research Institute where physicians and scientists from both the Cleveland Clinic and the School of Medicine have historically worked closely together to focus cutting edge research upon the causes and treatments of human illness. Second, a novel core curriculum has been designed to provide a solid foundation in basic scientific principles presented in the context of human organ systems and disease. Faculty research presentations, lab rotations, student research seminars, and an annual program showcase reinforce the translational application and potential clinical impact of the basic scientific principles throughout training. Third, the Training Program contains a broad range of trainers heading outstanding translational research laboratories in which our trainees perform rotations and thesis work. The range and strength of these laboratories, their collaborative interactions, and the commitment of the trainers to support of the Training Program is evidence of the collegial scientific environment within the Training Program. Finally, to ensure that each of the trainees comes to understand the clinical aspects of their area of investigation, each selects a Clinical Co-Mentor who helps organize an individual clinical experience. Through this experience trainees are introduced to patient diagnosis and treatment on a first hand basis. The Clinical Co-Mentor remains on the student’s thesis committee through graduation. In addition, the Program has been at the forefront in including program evaluation, responsible conduct of research training, rigor and reproducibility training, sexual harassment awareness, individual development plans, and career/professional development seminars that provide information about diverse career pathways. This proposal seeks funding for 6 trainees within the Training Program. This Training Program has gained national recognition and has had excellent outcomes. Since our first class matriculated in 2007 there has been a total of 55 PhD graduates with an average time to degree of 5.38 years. Our trainees preparing to take their places in diverse roles in the biomedical workforce, including as the leaders of the next generations of NIH funded laboratories translating basic scientific principles to address patient needs.

凯斯西储大学分子医学培训项目 医学专门旨在将医学知识引入研究生培训和 它是极少数独立的研究之一。 美国的分子医学博士课程利用四个因素。 首先，创建一个特别适合此目的的环境。 勒纳研究所聚集了来自克利夫兰诊所和 医学院历来密切合作，专注于前沿研究 其次，研究了人类疾病的原因和治疗方法。 旨在为在以下背景下提出的基本科学原理提供坚实的基础 人体器官系统和疾病。教师研究报告、实验室轮换、学生。 研究研讨会和年度项目展示强化了转化应用和 潜在临床影响贯穿整个培训的基本科学原则。 计划包含广泛的培训师，领导杰出的转化研究 我们的学员进行轮换和论文工作的实验室 范围和强度。 这些实验室、它们的协作互动以及培训师支持的承诺 培训计划的内容是培训中大学科学环境的证据 最后，确保每个学员都能了解临床方面的知识。 根据他们的研究领域，每个人都会选择一名临床合作导师来帮助组织个人 通过这种体验，学员将了解患者的诊断和治疗。 临床导师仍对学生的论文进行第一手治疗。 此外，该计划在包括在内方面一直处于领先地位。 项目评估、负责任的研究培训、严谨性和可重复性培训， 性骚扰意识、个人发展计划和职业/专业 提供有关不同职业道路信息的发展研讨会。 为培训计划中的 6 名学员寻求资金 该培训计划已获得资助。 自2007年第一届入学以来，我们得到了国家的认可，并取得了优异的成绩。 共有博士毕业生55人，平均获得学位时间5.38年。 学员准备在生物医学队伍中扮演不同的角色，包括 NIH 资助的下一代实验室的领导者翻译了基础科学 满足患者需求的原则。