Bioengineering Cardiovascular Training Grant (BCTG)

生物工程心血管培训补助金 (BCTG)

• 批准号: 10418471
• 负责人: MICHAEL REGNIER
• 金额: $ 19.98万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10418471
• 关键词: Biomedical Engineering; Cardiovascular system; Grant; Training

ABSTRACT The Bioengineering Cardiovascular Training Grant (BCTG) program provides Bioengineering training for six NIH supported and one Bioengineering department supported PhD students committed to careers in cardiovascular research. Cardiovascular (CV) diseases are the leading cause of mortality in the US and progress in this area will require training outstanding scientists with a variety of backgrounds in bioengineering to develop new and innovative approaches for study, diagnosis and treatment of CV disease. The UW and Department of Bioengineering have been leaders in CV research and technology development for over 50 years. BCTG faculty in multiple departments in the College of Engineering and School of Medicine have strong collaborative programs in this area. Our program benefits the public by training professionals in basic science and translational research that integrates engineering, mathematics, chemistry, physiology, physics and computational skills to promote fundamental discoveries and develop new technologies. Students gain interdisciplinary skills and the value of collaboration. The program emphasizes new technology development in diagnostics and therapeutics to study and treat CV pathologies, improving early detection and disease management, to improve quality of life for heart failure patients. We believe that the success of translational research requires highly trained scientists to be placed in both academia and industry, with skills to successfully transition research from universities to commercialization and the clinic. For this renewal proposal we have added several novel components to provide training in research and professional skills that spans the biomedical pipeline from discovery & mechanistic studies to translational research to commercialization or clinical development. The 2-year program involves 1) research in the laboratory of a chosen mentor, 2) a unique curriculum with opportunities for training in clinical translation and commercialization, and 3) clinical preceptorships that are unique to our program. Trainees attend a weekly seminar series focused on CV research, with an associated journal club and special sessions with speakers that are limited to trainees. Trainees also attend lectures and discussion groups in the Biomedical Research Integrity summer program, sponsored by the School of Medicine. Additional new components include outreach and research mentoring to under-represented groups to increase the diversity of the workforce in STEM fields, and a course that provides resources and seminars for professional skills development and training in research reproducibility, rigor and transparency. Trainees are selected based on strong quantitative and engineering backgrounds, training environment of faculty mentors, appropriateness of the research to our programmatic focus and the potential for innovative, collaborative and translational research. Trainees present at yearly symposiums and national meetings, and write a yearly progress report that includes feedback questions to continually improve our program. Trainees are required to apply for fellowships at the end of the two-year training period to begin establishing a record of successful competition in gaining research support.

抽象的 生物工程心血管培训补助金 (BCTG) 计划为六个 NIH 提供生物工程培训 支持和一个生物工程系支持致力于心血管事业的博士生 研究。心血管 (CV) 疾病是美国死亡的主要原因以及该领域的进展 将需要培训具有各种生物工程背景的杰出科学家来开发新的和 心血管疾病研究、诊断和治疗的创新方法。华盛顿大学和系 50 多年来，生物工程一直是 CV 研究和技术开发领域的领导者。 BCTG 师资队伍 工程学院和医学院多个院系有很强的合作项目 在这个区域。我们的计划通过培训基础科学和转化研究方面的专业人员来造福公众 整合了工程、数学、化学、生理学、物理和计算技能，以促进 基本发现并开发新技术。学生获得跨学科技能和价值 合作。该计划强调诊断和治疗方面的新​​技术开发以供研究 治疗心血管疾病，改善早期检测和疾病管理，以提高心脏的生活质量 失败患者。我们相信，转化研究的成功需要训练有素的科学家 位于学术界和工业界，具有成功地将研究从大学转移到工业界的技能 商业化和临床。对于这个更新提案，我们添加了几个新颖的组件来提供 研究和专业技能培训，涵盖从发现到机械的生物医学管道 研究到转化研究再到商业化或临床开发。为期 2 年的计划包括 1) 在选定导师的实验室进行研究，2）独特的课程，提供临床培训机会 翻译和商业化，以及 3) 我们项目独有的临床指导。学员参加 每周一次的系列研讨会，重点关注简历研究，并设有相关的期刊俱乐部和特别会议 演讲者仅限于实习生。学员还参加生物医学中心的讲座和讨论小组 研究诚信暑期项目，由医学院赞助。其他新组件包括 对代表性不足的群体进行外展和研究指导，以增加 STEM 劳动力的多样性 领域，以及为专业技能发展和培训提供资源和研讨会的课程 研究的可重复性、严谨性和透明度。受训人员的选择基于强有力的定量和 工程背景、教师导师的培训环境、研究对我们的适用性 计划重点以及创新、合作和转化研究的潜力。学员在场 在年度研讨会和国家会议上，撰写包含反馈问题的年度进度报告 不断改进我们的计划。学员必须在两年期结束时申请奖学金 培训期间开始建立获得研究支持的成功竞争记录。