Administrative Core

行政核心

• 批准号: 10415965
• 负责人: Scott Kopetz
• 金额: $ 26.82万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-08-20 至 2024-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10415965
• 关键词: Address; Adherence; Administrator; Advocate; Awareness; Bioinformatics; Biometry; Budgets; Cancer Center; Cancer Center Support Grant; Cancer Patient; Catchment Area; Center Core Grants; Clinical; Clinical Trials; Collaborations; Colorectal Cancer; Communication; Communities; Consult; Consultations; Country; County; Data Linkages; Decision Making; Deposition; Development; Ensure; Environment; Expenditure; Extramural Activities; Funding; Goals; Grant; Human Resources; Infrastructure; Institution; Joints; Leadership; Malignant Neoplasms; Malignant neoplasm of gastrointestinal tract; Malignant neoplasm of pancreas; Manuscripts; Medical center; Minority; Mission; Monitor; Pathology; Patient advocacy; Patients; Preparation; Progress Reports; Quality Control; Regulation; Reporting; Research; Research Activity; Research Personnel; Research Project Grants; Sampling; Site; System; Texas; Time; Translating; Translational Research; Underrepresented Minority; Universities; Woman; anticancer research; career; data access; data exchange; data integration; data integrity; data quality; data sharing; design; experience; medically underserved; meetings; minority communities; multidisciplinary; operation; programs; quality assurance; translational research program; underserved community

ADMINISTRATIVE CORE: Abstract/Summary The Administrative Core (AC) will provide all of the administrative and budgetary support to the MD Anderson Cancer Center Cancer SPORE in Gastrointestinal Cancers PIs and investigators, and form the central “hub” for productive interactions within the SPORE community. It is co-directed by Drs. Scott Kopetz and Anirban Maitra, and supported by a research program manager, Dr. David Menter, an experienced multi-investigator grant administrator and investigator. Both, Dr Kopetz and Dr. Maitra have experience in overseeing multi-investigator grants that include Institutional Grants, Cancer Center Core Grant Programs, and Stand Up to Cancer Grants. The overall goal of the AC will be coordination and monitoring of 3 Projects, 2 additional Cores, as well as the Developmental Research (DRP) and Career Enhancement (CEP) Programs. The AC is designed to monitor research activity and provide stable and continuous leadership and direction that advances integration, communication, and collaboration among GI SPORE investigators within MD Anderson and among extramural institutions, in particular, our partner institution, Johns Hopkins University (JHU). The AC will leverage the wideranging scientific, research, and SPORE-related experience of both Internal and External Advisory Boards in critical decision-making steps. The AC will ensure fiscal management, including personnel, budgets, and effort oversight, facilitate communication, interfacing with patient advocates, organization of meetings, manuscript preparation, and progress and other reports to the NCI and GI SPORE committees, and cross-communication of Cores and Programs. Of paramount importance is to ensure timely communication and consultation with the NCI Translational Research Program Director and staff for both adherence and deviations from stated programmatic goals. This Core is to also monitor scientific integrity and overall compliance with all institutional, state, federal, and NCI regulations and requirements, as well as quality assurance for data integrity including a change in the data integration plan with utilization of the new institutional clinical trial management system (CTMS) in lieu of Redcap, which provides greater data linkage residing in the Biospecimen and Pathology Core (Core 1) and Biostatistics and Bioinformatics Core (Core 2). The AC will be responsible for oversight of DRP and CEP for completion of deliverables. The AC also facilitates routine convening of staff and management of all necessary meetings. The AC will also enhanced awareness of colorectal and pancreatic cancer research and patient advocacy in the community as well as ongoing needs of minority and underserved communities in Houston and Harris County catchment area. This core will also help leverage and facilitate translational GI cancer research efforts being conducted by extramural groups locally and in the US and globally through both horizontal and vertical collaborations within the SPORE framework.

行政核心：摘要/总结 行政核心 (AC) 将为 MD 安德森中心提供所有行政和预算支持 癌症中心癌症孢子在胃肠道癌症 PI 和研究人员中的应用，并形成了中心“中心” SPORE 社区内的富有成效的互动由 Scott Kopetz 和 Anirban Maitra 博士共同指导。 并得到了研究项目经理 David Menter 博士的支持，他是一位经验丰富的多位研究者资助者 Kopetz 博士和 Maitra 博士都有监督多名研究者的经验。 赠款包括机构赠款、癌症中心核心赠款计划和抗击癌症赠款。 AC 的总体目标是协调和监督 3 个项目、2 个附加核心以及 AC 旨在监控发展研究 (DRP) 和职业提升 (CEP) 计划。 研究活动并提供稳定和持续的领导和方向，以促进整合的发展， MD 安德森中心和校外的 GI SPORE 研究人员之间的沟通和协作 AC 将利用内部和外部顾问委员会广泛的科学、研究和 SPORE 相关经验。 审计委员会将确保财务管理，包括人员、预算和工作量。 监督、促进沟通、与患者倡导者互动、组织会议、手稿 向 NCI 和 GI SPORE 委员会提交准备工作、进展情况和其他报告，以及交叉沟通 最重要的是确保与核心和计划的及时沟通和协商。 NCI 转化研究项目主任和工作人员遵守和偏离规定的情况 该核心还旨在监控所有机构的科学完整性和总体合规性。 州、联邦和 NCI 法规和要求，以及数据完整性的质量保证，包括 利用新的机构临床试验管理系统改变数据集成计划 (CTMS) 代替 Redcap，它提供了生物样本和病理学中更大的数据链接 核心（核心 1）和生物统计学和生物信息学核心（核心 2）将由审计委员会负责监督。 用于完成可交付成果的 DRP 和 CEP 还有助于员工和管理层的例行召集。 委员会还将提高对结直肠癌和胰腺癌研究的认识。 和患者在社区中的倡导以及少数民族和服务不足社区的持续需求 休斯顿和哈里斯县的集水区也将有助于利用和促进地理标志的转化。 当地、美国和全球的校外团体通过以下方式开展癌症研究工作： SPORE 框架内的横向和纵向合作。