Development and Testing of MyPEEPS Mobile for Young Transgender Men

为年轻跨性别男性开发和测试 MyPEEPS Mobile

基本信息

批准号：
10407736
负责人：
Robert Garofalo
金额：
$ 34.15万
依托单位：
COLUMBIA UNIVERSITY HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-01-01 至 2024-11-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10407736
关键词：
18 year old 19 year old AIDS prevention Address Adolescent and Young Adult Behavior Behavior Therapy Behavioral Birth Caricatures Clinical Cohort Studies Data Development Enabling Factors Epidemiology Face Family Feedback Female Focus Groups Future Gender Identity Goals HIV HIV Infections Health High Prevalence Human immunodeficiency virus test Individual Intervention Interview Literature Mechanics Methodology Methods New York City Population Predisposing Factor Prevalence Prevention Prevention program Principal Investigator Public Health Randomized Controlled Trials Reinforcing Factor Reporting Research Risk Risk Behaviors Sampling Science Sexual Health Sexually Transmitted Diseases Site Testing Time United States Work Youth base cis-male cisgender condomless anal sex efficacy study efficacy trial experience feasibility testing health care service health outcome disparity high risk high risk behavior improved interest mHealth male minority children mobile application mobile computing multidisciplinary novel peer pre-exposure prophylaxis preventive intervention response scale up sex sexual debut sexual minority sexual minority men social therapy design transgender transgender men transgender women uptake usability young men who have sex with men

项目摘要

PROJECT SUMMARY Transgender youth in the United States have unique health needs but often face barriers to accessing and receiving health care services which contribute to disparate health outcomes including high vulnerability to HIV and other sexually transmitted infections. Emerging evidence has begun to document HIV-related sexual risk among young transgender men (YTM), as well as low uptake of pre-exposure prophylaxis among those with indications, suggesting high vulnerability to HIV infection. Despite the high prevalence and increased risk of HIV in YTM who have sex with cisgender men, only one prior HIV prevention intervention has been developed to address the specific sexual health needs of YTM, which indicates a critical gap in HIV prevention science. In response to this need, and building off our strong preliminary work, we propose to develop a mobile intervention for YTM building on MyPEEPS Mobile, which was originally developed for very young sexual minority men. Central to this intervention is the premise that it will be delivered to youth during a developmental period that precedes or coincides with sexual debut, an important time for intervention, prior to or concurrent with initiation of high-risk behaviors. Given both the gap in HIV prevention science and the lack of current targeted interventions, and building upon our multidisciplinary team’s extensive experience in HIV prevention, mHealth, behavioral interventions, randomized controlled trials, and transgender health, we propose the following specific aims: 1) Using qualitative methodology, expert feedback, and usability assessments, develop MyPEEPS Mobile for YTM, 2) Conduct a pilot randomized controlled trial to examine the feasibility, acceptability, and preliminary efficacy of the revised MyPEEPS Mobile App in a sample of 80 YTM (15-19 years) and refine the study methods for a future efficacy trial, and 3) Assess predisposing, enabling, and reinforcing factors for MyPEEPS Mobile among YTM through theoretically-guided in-depth interviews. The proposed MyPEEPS intervention for YTM is a novel and evidence-driven intervention using mobile technology to deliver HIV prevention information to high-risk youth. This will be the first study to develop and pilot a scaled- up, mobile HIV prevention intervention designed by, and piloted for, a diverse group of YTM. The final product of this study will be the basis for an R01 application to conduct a large-scale efficacy study for this population. The proposed MyPEEPS Mobile intervention for YTM is a novel and evidence-driven intervention using mobile technology to deliver HIV prevention information specifically developed for YTM. Consequently, we are confident that the proposed intervention will be of high impact intervention for improving HIV prevention behaviors in YTM and have long-term implications for overall improvement in the public’s health.

项目概要美国的跨性别青年有独特的健康需求，但常常面临获得和获得健康服务的障碍。接受的医疗保健服务会导致不同的健康结果，包括高度感染艾滋病毒和其他性传播感染的证据已开始记录与艾滋病毒相关的性风险。年轻跨性别男性 (YTM) 的患病率以及患有此类疾病的人对暴露前预防的接受率较低迹象表明，尽管艾滋病毒感染率很高且风险增加，但仍很容易感染艾滋病毒。 YTM 中与顺性别男性发生性行为的艾滋病毒，仅制定了一项艾滋病毒预防干预措施以满足 YTM 的特定性健康需求，这表明艾滋病毒预防科学方面存在严重差距。为了满足这一需求，并在我们强有力的前期工作的基础上，我们建议开发一个移动基于 MyPEEPS Mobile 的 YTM 干预，该移动最初是为非常年轻的性行为开发的这项干预措施的核心前提是，该干预措施将在青年人处于发展阶段时进行。首次性行为之前或同时发生的时期，干预的重要时间，之前或同时鉴于艾滋病毒预防科学方面的差距和当前缺乏的措施。有针对性的干预措施，并以我们的多学科团队在艾滋病毒预防方面的丰富经验为基础，移动健康、行为干预、随机对照试验和跨性别健康，我们提出遵循具体目标： 1) 使用定性方法、专家反馈和可用性评估，开发 MyPEEPS Mobile for YTM，2) 进行试点随机对照试验以检验可行性，修订后的 MyPEEPS 移动应用程序在 80 个 YTM 样本中的可接受性和初步功效（15-19 年）并完善未来疗效试验的研究方法，以及 3）评估诱发、促成和通过理论指导的深入访谈，了解 YTM 中 MyPEEPS Mobile 的强化因素。拟议的 YTM 的 MyPEEPS 干预是一种使用移动技术的新颖且证据驱动的干预措施向高危青少年提供艾滋病毒预防信息这将是第一项开发和试点大规模的研究。最终产品是由 YTM 的不同群体设计并试点的移动艾滋病毒预防干预措施。这项研究的结果将成为 R01 应用程序的基础，以针对该人群进行大规模功效研究。拟议的 YTM 的 MyPEEPS 移动干预是一种使用移动设备的新颖且证据驱动的干预措施专门为 YTM 开发的提供艾滋病毒预防信息的技术经过测试。相信拟议的干预措施将对改善艾滋病毒预防产生重大影响 YTM 中的行为并对公众健康的整体改善产生长期影响。