Administrative Core

行政核心

• 批准号: 10404140
• 负责人: ROBERT A. LAFYATIS
• 金额: $ 15.9万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-20 至 2027-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10404140
• 关键词: Advisory Committees; Area; Basic Science; Biological Markers; Biology; Blood Vessels; Boston; Budgets; Clinical; Collaborations; Communication; Critiques; Disease; Ensure; Environment; Evaluation; Fostering; Goals; Grant; Human Resources; Immunology; Individual; Interstitial Lung Diseases; Lead; Leadership; Lung; Medicine; Mentors; Minority; Mission; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Outcome; Pathogenesis; Patients; Physicians; Program Reviews; Recommendation; Reporting; Research Personnel; Science; Scientist; Site; Skin; Structure; System; Systemic Scleroderma; Systems Biology; Time; Translational Research; Universities; experience; meetings; minority investigator; novel therapeutics; programs; pulmonary arterial hypertension; skin disorder; translational study; web site

The Administrative Core will enable the whole to be greater than the parts by fostering a scientific environment that promotes the overall CORT objectives: advancing understanding of systemic sclerosis (SSc) pathogenesis, to identifying new biomarkers of disease, and discovering novel therapies for patients with SSc. Dr. Robert Lafyatis will lead the CORT as Program Director and chair the Executive Committee, composed of the directors and associate directors of each of the projects and cores with Dr. Robyn Domsic the Program Associate Director. Dr. Oliver Eickelberg, U Pitt Vice Chair for Basic and Translational Science (project 2, PI); Dr. Stephen Chan, Director, Center for Pulmonary Vascular Biology and Medicine (project 3, PI); and Dr. Harinder Singh, Director of the Center for Systems Immunology (Core C, PI) will provide additional leadership experience for the Executive Committee. The administrative core will organize Executive Committee meetings every other month that will serve both as a time to discuss administrative organization, but more importantly a time for scientific exchange between investigators. The Administrative Core will assemble a highly-experienced external Advisory Committee composed of physician-scientists, working in the areas of CORT projects and cores: SSc skin disease, interstitial lung disease, pulmonary arterial hypertension, biomarkers, systems biology and clinical outcomes. This committee will annually review each project and core, critiquing progress, probing obstacles, and providing advice for new scientific directions. The CORT Administrative Core will manage budgets, arrange meetings of the Executive and Advisory committees, assist the CORT director in preparing reports, manage the website, solicit and organize review of Pilot and Feasibility proposals, and arrange enrichment seminars. The Center will organize the structures needed for robust communication in order to advance the science of the interdisciplinary groups composing the Center. The Administrative Core will provide enrichment opportunities for CORT investigators through invited speakers; solicit and organize Advisory Committee evaluation of Pilot and Feasibility Grants, targeting young, early stage and minority investigators; and organize mentoring for minority, young, early stage investigators

行政核心将通过培育科学环境使整体大于部分 促进 CORT 的总体目标：增进对系统性硬化症 (SSc) 的了解 发病机制，识别疾病的新生物标志物，并发现 SSc 患者的新疗法。 Robert Lafyatis 博士将作为项目总监领导 CORT 并担任执行委员会主席，该委员会由以下人员组成： 每个项目和核心项目的主任和副主任与 Robyn Domsic 博士一起参与该项目 副主任。 Oliver Eickelberg 博士，皮特大学基础与转化科学副主席（项目 2，PI）； Stephen Chan博士，肺血管生物学与医学中心主任（项目3，负责人）；和博士。 系统免疫学中心主任（核心 C，PI）Harinder Singh 将提供额外的领导 执行委员会的经验。行政核心将组织执行委员会会议 每隔一个月，这既可以作为讨论行政组织的时间，但更重要的是 研究人员之间进行科学交流的时间。行政核心将组建一支经验丰富的团队 外部咨询委员会由从事 CORT 项目和研究领域的医师科学家组成 核心：SSc皮肤病、间质性肺病、肺动脉高压、生物标志物、系统生物学 和临床结果。该委员会将每年审查每个项目和核心，批评进展，探究 障碍，并为新的科学方向提供建议。 CORT 管理核心将管理 预算，安排执行委员会和咨询委员会会议，协助 CORT 主任准备 报告，管理网站，征求并组织试点和可行性建议的审查，并安排 丰富研讨会。该中心将组织强有力的沟通所需的结构，以便 促进组成该中心的跨学科小组的科学发展。行政核心将提供 通过受邀演讲者为 CORT 研究人员提供丰富的机会；征求并组织咨询 委员会对试点和可行性补助金的评估，针对年轻、早期和少数族裔研究人员； 并为少数族裔、年轻的早期研究人员组织指导