NorthStar Node of the Clinical Trials Network: Facebook intervention for preventing opioid relapse among American Indian Women

临床试验网络 NorthStar 节点：Facebook 干预美国印第安妇女预防阿片类药物复发

• 批准号: 10391905
• 负责人: GAVIN BART
• 金额: $ 23.87万
• 依托单位: HENNEPIN HEALTHCARE RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-04-15 至 2022-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10391905
• 关键词: Abstinence; Address; Adopted; Adoption; Adult; Advisory Committees; Affect; Alaska Native; American Indians; Biological; COVID-19 pandemic; Clinical Trials Network; Communities; Development; Effectiveness of Interventions; Facebook; Funding; Future; Gender; Generations; HIV; Hepatitis C; Individual; Intervention; Intervention Trial; Interview; Lead; Minnesota; Modeling; Morbidity - disease rate; Opioid; Overdose; Participant; Pharmacotherapy; Phase; Population; Public Health; Randomized; Recovery; Relapse; Research; Resources; Sampling; Social Network; Social support; Stress; Technology; Telephone; Testing; Time; Trauma; Woman; Work; addiction; base; care providers; control trial; coping; cultural values; design; digital; disorder later incidence prevention; evidence base; healthcare community; innovation; medication-assisted treatment; men; mortality; opioid use; opioid use disorder; perceived stress; prescription opioid; prevent; preventive intervention; prototype; recruit; resilience; social; social media; stress management; stress reactivity; substance use; virtual

PROJECT SUMMARY In 2017, American Indian and Alaska Native (AIAN) adults in Minnesota (MN) were six times more likely to die of an overdose involving opioids than whites, representing the greatest disparity observed between AIAN and whites in the US. Medication for opioid use disorder (MOUD) is an evidence-based approach, and strategies to promote continuation of pharmacotherapy and support OUD recovery are important. Gender- specific factors affecting opioid use relapse and recovery that are more prevalent in women compared with men include perceived stress, trauma, and social support for abstinence. AIAN gender-specific interventions for OUD do not exist. Research has documented the positive impact of social networks and social support on abstinence from substance use. However, understanding how best to leverage social support remains a key challenge for the addiction’s treatment field. We propose to address these gaps by developing a social digital (Facebook) intervention to promote stress management and social network support for opioid abstinence among AIAN women. Virtual digital platforms have potential for greater reach and scale. Consistent with the AIAN cultural value of interdependence, social media-formed groups to prevent opioid relapse could lead to greater adoption and sustainability by encouraging collaborative efforts across generations of AIAN women and leveraging community resilience for coping with stress. The overall objective of this one-year, Phase I, pilot preparatory study is to develop and beta-test a Facebook intervention for reducing opioid relapse among AIAN women. This project was designed with community partners at the MN Indian Women’s Resource Center (MIWRC). A study-specific community advisory committee will guide all project activities. The Specific Aim is to develop and beta-test the Facebook intervention content and prototype. In this formative work, we will conduct individual qualitative interviews by phone/video with a purposefully recruited sample of AIAN women with OUD, with at least one month of abstinence and receiving MOUD (n=12); as well as addiction care providers and AIAN community stakeholders (n=12). Participants will provide input on the cultural relevance and perceived effectiveness of intervention content. A Facebook intervention prototype will be developed, beta-tested, and iteratively refined with AIAN women (n=10). Results will inform development of a future pilot randomized control trial of the intervention. This project is innovative for developing a gender-specific, socially based, opioid relapse prevention intervention using social media technologies that are culturally relevant and already adopted. This proof-of-concept study is the first step to an intervention that could ultimately be widely disseminated through addiction health care and community-based settings as well as social media; and serve as a model for developing social digital addictions treatment in other populations, enhancing overall reach and impact.

项目概要 2017 年，明尼苏达州 (MN) 的美洲印第安人和阿拉斯加原住民 (AIAN) 成年人患此病的可能性是其他人的六倍 死于阿片类药物过量的人数高于白人，这是 AIAN 之间观察到的最大差异 在美国，针对阿片类药物使用障碍 (MOUD) 的药物治疗是一种基于证据的方法，并且 促进继续药物治疗和支持 OUD 恢复的策略很重要。 影响阿片类药物使用复发和恢复的具体因素与女性相比更常见 男性包括感知压力、创伤和对 AIAN 针对性别的干预措施的社会支持。 不存在 OUD 的研究记录了社交网络和社会支持的积极影响。 然而，了解如何最好地利用社会支持仍然是关键。 我们建议通过开发社交数字技术来解决这些差距。 (Facebook) 促进压力管理和社交网络支持阿片类药物戒断的干预措施 在 AIAN 女性中，虚拟数字平台具有更大的影响力和规模。 AIAN 相互依存的文化价值，社交媒体形成的防止阿片类药物复发的群体可能会导致 通过鼓励几代 AIAN 女性的协作努力，提高采用率和可持续性 利用社区复原力应对压力 这一为期一年的第一阶段试点的总体目标。 准备研究的目的是开发和测试 Facebook 干预措施，以减少 AIAN 中的阿片类药物复吸 该项目是与明尼苏达州印第安妇女资源中心的社区合作伙伴共同设计的。 (MIWRC)。特定研究的社区咨询委员会将指导所有项目活动。 在这项形成性工作中，我们将开发并测试 Facebook 干预内容和原型。 通过电话/视频对特意招募的具有 OUD 的 AIAN 女性样本进行个人定性访谈， 戒毒至少一个月并接受 MOUD（n = 12）以及戒瘾护理提供者和 AIAN 社区利益相关者 (n=12) 参与者将提供有关文化相关性和感知的意见。 干预内容的有效性将被开发、测试和测试。 与 AIAN 女性 (n=10) 一起反复完善。 结果将为未来的干预随机对照试验的开发提供信息。 利用社会因素制定针对特定性别、基于社会的阿片类药物复吸预防干预措施的创新 这项概念验证研究是第一项与文化相关且已被采用的媒体技术。 最终可以通过成瘾医疗保健和 基于社区的环境和社交媒体；并作为发展社交数字化的模型 对其他人群进行毒瘾治疗，增强整体影响力。