Regional Centre for Vector Borne Diseases in West Africa (RCVBD)

西非媒介传播疾病区域中心 (RCVBD)

• 批准号: 10377584
• 负责人: YAW ASARE AFRANE
• 金额: $ 24.84万
• 依托单位: UNIVERSITY OF GHANA
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-03-16 至 2026-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10377584
• 关键词: Africa; African; Anti-malarial drug resistance; Area; Artemisinins; Bioinformatics; Burkina Faso; California; Communicable Diseases; Communities; Developed Countries; Disease model; Educational workshop; Entomology; Epidemiology; Faculty; Fostering; Gambia; Genetic; Genomics; Ghana; Goals; Health; Insecticide Resistance; Institution; Intervention; Knowledge; Malaria; Medical Entomology; Medical Research; Mentorship; Modeling; Molecular; New Mexico; Pharmaceutical Preparations; Population; Population Genetics; Productivity; Publications; Research; Research Training; Science; Scientist; Techniques; Training; Training Programs; Universities; Vector-transmitted infectious disease; career; doctoral student; faculty research; malaria transmission; next generation; skills; tool

PROJECT SUMMARY Although West Africa is currently burdened with an unprecedented high levels of malaria, the research capacity in Africa is too low to meet the malaria control and elimination goal. Furthermore, many new techniques and tools developed in the developed countries have not been well utilized by Africa scientists. For example, new tools in molecular population genetics, genomics and bioinformatics and disease modeling have not been integrated into malaria research and control in Africa. Low research capacity in West Africa is far more dire in comparison to other African regions. Therefore, there is an immediate need to strengthen the research capacity in infectious diseases in West Africa. We propose this Regional Centre for Vector Borne Diseases in West Africa (RCVBD) to enhance research capacity in malaria epidemiology and medical entomology through training PhD students and junior faculty and research scientists. The consortium partners are from three West African institutions (University of Ghana, The Medical Research Council Unit Gambia, and Institut de Recherche en Sciences de la Santé of Burkina Faso). Collaborators from three US institutions (University of California at Irvine, University of New Mexico and the Northwestern University) will assist the training program. The overall goal of this training program is to enhance research capacity in West Africa by training the next generation of African scientists in the area of vector-borne disease research and control with a special focus on malaria. The thematic areas of training include epidemiology, medical entomology and application of new genetic, genomic and ecological research tools. We propose three tracks of training. Track 1 will be long-term training of 8 PhD students in West Africa. Track 2 will provide short- term research training to 15 junior university faculty and junior scientists from the Ministry of Health in West Africa to foster specific skills required for malaria research and control. Track 3 will be training workshops and short courses to disseminate techniques and knowledge to wide communities involved in vector borne disease research and control in West Africa. This training program will focus on four scientific areas in urgent need, including 1) new tools for malaria epidemiological and entomological surveillance, 2) antimalarial drug resistance to artemisinin and partner drugs, 3) population genomics of insecticide resistance, and 4) modeling malaria transmission dynamics and malaria intervention strategies. This research training program will help advance the careers of West African scientists by strengthening their academics and research productivity through vigorous mentorship and outstanding publications, equipping them with new knowledge and skills, and enhancing their collaborative opportunities with scientists within and out of Africa.

项目概要 尽管西非目前疟疾发病率空前高涨，但研究 非洲的能力太低，无法实现控制和消除疟疾的目标。此外，还有许多新的目标。 发达国家开发的技术和工具尚未被非洲很好地利用 例如，分子群体遗传学、基因组学和生物信息学方面的新工具以及 非洲的疾病模型尚未纳入疟疾研究和控制中。 与其他非洲地区相比，西非的能力要严峻得多。 我们建议迫切需要加强西非传染病的研究能力。 西非媒介传播疾病区域中心 (RCVBD) 旨在提高研究能力 通过培训博士生和初级教师，在疟疾流行病学和医学昆虫学领域开展研究 该联盟的合作伙伴来自三个西非机构（西非大学）。 加纳、冈比亚医学研究理事会单位和Institut de Recherche en Sciences de la 来自布基纳法索的 Santé）的合作者来自三个美国机构（加州大学欧文分校， 新墨西哥大学和西北大学）将协助培训计划。 该培训计划的目标是通过培训下一代来增强西非的研究能力 在媒介传播疾病研究和控制领域培养了一代非洲科学家 培训的主题领域包括流行病学、医学昆虫学。 我们提出了新的遗传、基因组和生态研究工具的三个方向。 培训。轨道 1 将在西非提供 8 名博士生的长期培训。 为卫生部 15 名初级大学教师和初级科学家提供短期研究培训 西非培养疟疾研究和控制所需的具体技能将是培训。 举办讲习班和短期课程，向广泛参与的社区传播技术和知识 该培训计划将重点关注四个方面。 迫切需要的科学领域，包括1）疟疾流行病学和昆虫学新工具 监测，2) 抗疟药物对青蒿素和伙伴药物的耐药性，3) 群体基因组学 杀虫剂耐药性，4) 模拟疟疾传播动态和疟疾干预 该研究培训计划将通过以下方式帮助推动西非科学家的职业生涯。 通过积极的指导和杰出的人才来加强他们的学术和研究生产力 出版物，为他们提供新的知识和技能，并加强他们的合作 与非洲国内外科学家合作的机会。