Tai Chi intervention to improve chronic pain management for adults with HIV

太极拳干预可改善成人艾滋病毒感染者的慢性疼痛管理

基本信息

批准号：
10370307
负责人：
Eugene M Dunne
金额：
$ 15.66万
依托单位：
TEMPLE UNIV OF THE COMMONWEALTH
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-04-15 至 2024-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10370307
关键词：
AIDS-Related Opportunistic Infections Acquired Immunodeficiency Syndrome Acute Pain Address Adult Advertisements Applications Grants Award Behavior Behavior Therapy Behavioral Medicine Benchmarking Biological Boston Caring Chronic Clinic Clinical Clinical Research Clinical Trials Collaborations Communicable Diseases Complementary Medicine Control Groups Data Data Analyses Data Collection Development Disease Progression Environment Evaluation Fostering Funding Glean Goals Grant HIV HIV antiretroviral Health Health Care Costs Health Psychology Health education Home Hospitals Human Immunology Individual Injury Integrative Medicine Intervention Interview Joints K-Series Research Career Programs Knowledge Language Life Medical Medicine Mental Health Mentored Patient-Oriented Research Career Development Award Mentors Mentorship Meta-Analysis Methods Mind-Body Intervention Mind-Body Method NIH Office of AIDS Research National Center for Complementary and Integrative Health Nervous system structure Nurses Opioid Pain Pain Research Pain management Patient Self-Report Patients Persons Pharmaceutical Preparations Physicians Pilot Projects Population Prevalence Preventive Medicine Provider Psychiatry Qi Gong Qualitative Methods Quality of life Randomized Randomized Controlled Trials Research Research Personnel Resources Schedule Science Scientist Self Management Series Stigmatization Tai Ji Tissues Training United States United States National Institutes of Health Universities Video Recording Virus Vulnerable Populations Withholding Treatment acceptability and feasibility base body-mind career career development chronic pain chronic pain management chronic pain patient chronic painful condition comorbidity coping cost design disability efficacy testing evidence base experience faculty support immune function improved insight medical specialties neglect non-cancer chronic pain opioid misuse pain patient pain perception pain symptom pilot trial prescription opioid professor programs protocol development psychologic recruit response retention rate side effect skills substance use therapy design transportation access

项目摘要

PROJECT SUMMARY/ABSTRACT Candidate. I am excited to submit this application to NCCIH for a K23 Award. To date, I have received quality training as a scientist-practitioner in clinical health psychology, emphasizing research with HIV populations. To become an independent investigator with a research program focused on the use of mind-body interventions to manage chronic conditions, I require additional training in intervention design, implementation, and evaluation. Training Plan. My training goals for this K23 award include: 1) extend my knowledge of mind-body interventions for chronic pain management; 2) develop expertise regarding treatment for adults living with HIV and chronic pain; 3) cultivate advanced skills in clinical trial methods; 4) develop, implement, and evaluate a pilot trial of Tai Chi for chronic pain management among persons living with HIV; and 5) continue my professional development toward a successful career as an independently-funded investigator. Environment. During the award period, I will be an Assistant Professor in the Department of Psychiatry and Human Behavior (DPHB) at Brown University and Research Scientist at the Centers for Behavioral and Preventive Medicine (CBPM) of The Miriam Hospital. DPHB is among the top academic departments of psychiatry in the United States, with approximately 200 ongoing studies and $50 million in externally sponsored research. DPHB has an impressive track record of providing a suitable environment for the successful completion of K awards. CBPM provides an outstanding research environment that supports faculty in developing state-of-the-science, programmatic research by fostering a stimulating intellectual environment that encourages collaboration. Miriam Hospital is home to the Immunology Center, an urban HIV-clinic that provides comprehensive primary and specialty care for 1,700 HIV-infected patients, and is a major component of the Centers for AIDS Research (CFAR), a joint research effort between Brown and Boston Universities. Mentors. I have constructed an expert mentorship team, with leading scientists in the fields of mind-body research, behavioral interventions, HIV medicine, chronic pain management, and qualitative methods. Proposed Research. Consistent with the strategic priorities of NCCIH, the Office of AIDS Research, and NIH’s Federal Pain Research Strategy (FPRS), the proposed research addresses gaps in non-pharmacological chronic pain management in a neglected chronic pain group [i.e., people living with HIV (PLWH)]. I propose three research aims: 1) to understand perceived access, barriers, facilitators, and benefits related to Tai Chi for chronic pain among patients with HIV, in-depth qualitative interviews will be conducted with PLWH (N≈12-18) and providers (N≈6-10) at the Immunology Center; 2) optimize recruitment material for Tai Chi intervention and determine best format to deliver intervention based on information learned in qualitative study; and 3) to examine the feasibility and acceptability of Tai Chi for chronic pain management for PLWH, we will conduct a randomized pilot study (N = 40) of Qigong/Tai Chi Easy compared to a health education control group.

项目概要/摘要我很高兴向 NCCIH 提交 K23 奖申请。迄今为止，我已获得优质资格。作为临床健康心理学的科学家实践者接受培训，强调对艾滋病毒人群的研究。成为一名独立调查员，其研究项目专注于使用身心干预措施管理慢性病，我需要在干预设计、实施和评估方面接受额外的培训。培训计划。我的 K23 奖项的培训目标包括：1）扩展我的身心知识。慢性疼痛管理干预措施；2) 发展成人艾滋病毒感染者治疗方面的专业知识和慢性疼痛；3) 培养临床试验方法的高级技能；4) 开发、实施和评估对艾滋病毒感染者进行太极拳治疗慢性疼痛的试点试验，以及 5) 继续我的研究；作为一名独立资助的调查员，为职业生涯的成功提供专业发展。在获奖期间，我将担任精神病学和环境系的助理教授。布朗大学人类行为 (DPHB) 和行为与行为中心研究科学家 DPHB 的预防医学 (CBPM) 是顶尖的学术科室之一。美国精神病学领域，约有 200 项正在进行的研究和 5000 万美元的外部投资 DPHB 在为研究提供合适的环境方面有着令人印象深刻的记录。 CBPM 的成功完成为教师提供了良好的研究环境。通过营造激励性的智力环境来发展最先进的科学、规划性研究鼓励合作的米里亚姆医院是免疫学中心的所在地，这是一家城市艾滋病毒诊所，为 1,700 名 HIV 感染者提供全面的初级和专科护理，是一个主要组成部分艾滋病研究中心 (CFAR) 是布朗大学和波士顿大学的联合研究项目。我组建了一个专家指导团队，其中包括身心领域的顶尖科学家。研究、行为干预、艾滋病毒医学、慢性疼痛管理和定性方法。拟议的研究符合 NCCIH、艾滋病研究办公室和 NIH 的联邦疼痛研究战略 (FPRS)，拟议的研究解决了非药理学方面的空白我建议对被忽视的慢性疼痛群体（即艾滋病毒感染者（PLWH））进行慢性疼痛管理。三个研究目标：1）了解与太极拳相关的感知途径、障碍、促进因素和益处 HIV感染者的慢性疼痛，将对PLWH进行深入的定性访谈（N≈12-18）和免疫学中心的提供者（N≈6-10）；2）优化太极干预的招募材料和根据定性研究中学到的信息确定实施干预的最佳形式；以及 3) 检查太极拳用于 PLWH 慢性疼痛管理的可行性和可接受性，我们将进行一次气功/太极拳与健康教育对照组的随机试点研究（N = 40）。