Phase III COBRE: Multimodal Imaging of Neuropsychiatric Disorders (MIND)

III 期 COBRE：神经精神疾病 (MIND) 的多模态成像

基本信息

批准号：
10372242
负责人：
Andrew Robert Mayer
金额：
$ 37.39万
依托单位：
LOVELACE BIOMEDICAL RESEARCH INSTITUTE
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-05-18 至 2023-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10372242
关键词：
Algorithmic Analysis Appointment Area Awareness Biology Biometry Bipolar Depression Bipolar Disorder Brain Brain Diseases Brain imaging Businesses Centers of Research Excellence Chemistry Classification Collaborations Communities Complex Computers Core Facility Data Data Analyses Department of Energy Development Devices Diffusion Magnetic Resonance Imaging Dimensions Disease Electroencephalography Engineering Ensure Environment Equipment Faculty Functional Magnetic Resonance Imaging Funding Funding Agency Genetic Goals Grant Image Image Analysis Imaging technology Individual Infrastructure Institution Interdisciplinary Study Leadership Magnetic Resonance Imaging Magnetic Resonance Spectroscopy Magnetoencephalography Major Depressive Disorder Mental Depression Mental disorders Mentors Methods Mind-Body Method Mission Multimodal Imaging Neurobiology Neurologic Neurosciences New Mexico Paper Patients Peer Review Phase Pilot Projects Positioning Attribute Principal Investigator Program Development Psychiatry Publications Recording of previous events Research Research Domain Criteria Research Personnel Research Project Grants Research Training Resources Role Schizophrenia Seeds Site Structure System Teacher Professional Development Time Training Training Programs Translational Research United States National Institutes of Health Universities Vision base cohesion computer science computerized data processing data acquisition data management deep learning density design distinguished professor improved independent component analysis meetings multimodal data multimodality neuroimaging neuroinformatics neuromechanism neuropsychiatric disorder programs tool

项目摘要

Project Summary/Abstract This Phase III (P-III) COBRE project will extend the cores that have been successfully leveraged in our Phase I (P-I) and Phase II (P-II) COBRE projects and sustain these unique resources in New Mexico through the im- plementation of a business plan. Over the past eight years we have built up infrastructure and created a cutting edge brain imaging center, our P-II project is just over half-way through and is even more successful than our P- I was at this point in time. The Mind Research Network (MRN) houses an Elekta Neuromag 306-channel MEG System, a high density EEG lab, a 3T Siemens Trio MRI scanner, and a mobile 1.5T Siemens Avanto MRI scanner. Additional resources include a centralized neuroinformatics system, a strong IT management plan, and state-of-the-art image analysis expertise and tools. This P-III COBRE center will continue our momentum and move the cores we have developed into a position of long term sustainability. We will continue with the technical cores established during the P-II project including multimodal data acquisition (MDA), algorithm and data analy- sis (ADA), and biostatistics and neuro-informatics (BNI). These cores have begun to serve MRN and the greater community, as well as other institutions including extensive collaborations with IDeA funded projects in New Mexico and other states. We believe this P-III COBRE is extremely well-positioned to establish and sustain New Mexico as one of the premier brain imaging sites. We include an extensive pilot project program (PPP) that is built on the successful pilot programs implemented as part of the earlier COBRE phases. This includes an ex- tensive educational, mentoring, and faculty development program to carefully mentor and position faculty who use the cores to maximize their potential to successfully compete for external funding, thus fulfilling the ultimate goals of the COBRE program. 2

项目概要/摘要该第三阶段 (P-III) COBRE 项目将扩展我们阶段已成功利用的核心 I (P-I) 和第二阶段 (P-II) COBRE 项目，并通过以下方式维持新墨西哥州的这些独特资源：商业计划的实施。在过去的八年里，我们建立了基础设施并创建了切割边缘脑成像中心，我们的P-II项目刚刚进行了一半，甚至比我们的P-II还要成功我正处于这个时间点。心灵研究网络 (MRN) 拥有 Elekta Neuromag 306 通道 MEG 系统、高密度脑电图实验室、3T 西门子 Trio MRI 扫描仪和移动 1.5T 西门子 Avanto MRI 扫描器。其他资源包括集中式神经信息学系统、强大的 IT 管理计划以及最先进的图像分析专业知识和工具。这个 P-III COBRE 中心将继续我们的势头并将我们开发的核心转移到长期可持续发展的位置。我们将继续在技术上 P-II项目期间建立的核心包括多模式数据采集（MDA）、算法和数据分析 sis（ADA）以及生物统计学和神经信息学（BNI）。这些核心已经开始服务于 MRN 和更大的社区以及其他机构，包括与 IDeA 资助的新项目进行广泛合作墨西哥和其他州。我们相信 P-III COBRE 非常有能力建立和维持新的墨西哥是主要的脑成像地点之一。我们包括一个广泛的试点项目计划 (PPP) 建立在作为早期 COBRE 阶段的一部分实施的成功试点计划的基础上。这包括前任紧张的教育、指导和教师发展计划，认真指导和定位那些有能力的教师利用核心最大限度地发挥其潜力，成功竞争外部资金，从而实现最终目标 COBRE 计划的目标。 2