MEDICAL COMPLICATIONS AND PARENTING-PRETERM DEVELOPMENT

医疗并发症和育儿-早产

• 批准号: 2199398
• 负责人: SUSAN LANDRY
• 金额: $ 35.99万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
• 依托单位国家: 美国
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-09-06 至 1997-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2199398
• 关键词: behavior prediction; behavior test; central nervous system disorders; child behavior; child physical development; child rearing; disease /disorder proneness /risk; female; human subject; infant human (0-1 year); intelligence; longitudinal human study; low birth weight infant human; maternal behavior; medical complication; mother child interaction; neuropsychological tests; premature infant human; preschool child (1-5); psychomotor function; respiratory disorder; socioeconomics

Our current longitudinal study investigates the relation of early medical complications associated with prematurity to development through 24 mo in a large cohort of very low birth weight (VLBW) infants. In this competitive renewal application, assessments will be extended for the same group of infants to 36 and 48 mo of age. The ability of caretaking factors to facilitate or impede development in these children will continue to be evaluated. We will also investigate the relation of a group of maternal social and personal predictors to changes across time in the quality of mothers' parenting styles. The study will focus on the lower socioeconomic (SES) environment in which the increased likelihood of premature birth, combined with the developmental risks associated with negative social and parenting factors, place the infant at double jeopardy for poor outcome. The sample consists of 238 low SES, VLBW and 134 full term (FT) infants, matched for SES and maternal age. VLBW infants are subdivided into 2 risk groups (High risk = 100, Low risk = 138) according to the etiology and severity of their early medical complications. These complications ar all associated with central nervous system damage, which appears to result primarily from either focal brain lesion (e.g., intraventricular hemorrhage, periventricular leukomalacia) or from recurrent episodes of hypoxia secondary to respiratory disorders (e.g., respiratory distress syndrome, bronchopulmonary dysplasia). Specific medical complications are indexed so that their relation to infant development can be separately evaluated. The inclusion of a normal, FT group allows us to assess the degree to which infants of low or high medical risk differ in rates of development from infants with normal perinatal histories. The development of a broad range of skills and behaviors will be assessed at 6, 12, 24, 36 and 48 mo of age in conjunction with measures of maternal parenting styles and predictors of parenting. Our preliminary results at ages 6 and 12 mo show complex patterns of change in both infant and parent variables, and in their interactions, which differ significantly for the HR group. Examination of these differences at later timepoints will provide valuable information to help us design sensitive interventions which are timed and tailored to the unique developmental needs of HR infants, and also reflect the special needs and abilities of their low SES mothers.

我们目前的纵向研究调查了早期医学的关系 通过24 mo的发展与发展相关的并发症 大量的出生体重（VLBW）婴儿。在这个 竞争性更新申请，评估将进行相同的评估 小组的婴儿至36岁和48个月。护理因素的能力 促进或阻碍这些孩子的发展将继续 评估。 我们还将研究一组母亲的关系 社会和个人预测因时间的变化的质量 母亲的育儿风格。该研究将重点放在较低的社会经济上 （SES）早产可能性增加的环境， 与负面社会和负面的发展风险相结合 育儿因素，将婴儿置于双重危险中，以表现不佳。 该样品由238个低SES，VLBW和134个完整期（FT）婴儿组成， 匹配SES和产妇年龄。 VLBW婴儿被细分为2风险 根据病因和 他们早期医疗并发症的严重程度。这些并发症全部 与中枢神经系统损害相关，这似乎导致 主要来自局灶性脑病变（例如，脑室室内 出血，脑室白细胞膜）或反复发作​​的发作 继发于呼吸系统疾病的缺氧（例如，呼吸窘迫 综合征，支气管肺发育不良）。特定的医疗并发症是 索引使其与婴儿发育的关系可以分开 评估。包含正常的FT组允许我们评估 低或高医疗风险的婴儿的率差异 来自正常围产期历史的婴儿的发展。发展 在6、12、24、36中，将评估广泛的技能和行为 与母亲育儿风格的衡量标准结合使用48个月。 和育儿的预测因素。 我们在6岁和12个月的初步结果显示了复杂的模式 婴儿和父级变量及其相互作用的变化， 人力资源组有很大不同。检查这些 以后的时间点上的差异将提供有价值的信息以帮助 美国设计敏感的干预措施，定时并量身定制 人力资源婴儿的独特发展需求，也反映了特殊的 他们低矮的母亲的需求和能力。