Administration and Biostatistics Core

行政和生物统计学核心

• 批准号: 10327711
• 负责人: MACRAE F LINTON
• 金额: $ 19.03万
• 依托单位: VANDERBILT UNIVERSITY MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-06-01 至 2025-12-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10327711
• 关键词: Animals; Award; Bioinformatics; Biometry; Biostatistics Core; Budgets; Code; Communication; Data Analyses; Documentation; Ensure; Equipment; Expenditure; Experimental Designs; Grant; High Density Lipoproteins; Institutional Policy; Methods; Policies; Procedures; Reagent; Reporting; Reproducibility; Research Personnel; Seeds; Services; Supervision; Travel; Untranslated RNA; Validation; Work; human disease; human subject; meetings; model development; simulation

The purpose of the Administrative and Biostatistics Core (Core A) is to coordinate the administrative and fiscal activities of the PPG, to provide biostatistics support for all of the Projects, and to ensure rigorous experimental design and data analysis for all the Projects. Dr. Linton will provide oversight for all functions of Core A. Mr. Nicholas Jenkins, Grants Manager, will work closely with Dr. Linton to provide fiscal oversight and management of the budgetary aspects of the PPG’s Projects and Cores, including compliance with institutional policy and implementation of grant policy for post award management. Mr. Jenkins will assist with budgets related to grant submissions, including competing and noncompeting renewals. Ms. Lawrence will oversee the financial aspects of the administration of the budget. She will supervise and coordinate communication with the Grants Manager and the Administrative Officer. Maria Peng, Administrative Officer, will prepare monthly budget statements for the Projects and Cores for the Investigators. She will be responsible for PPG reports and administration of finances for the service Cores and the Projects. Ms. Lawrence and Ms. Bartkus, the administrative assistant, will be jointly responsible for generating purchase orders for equipment and reagents for all of the PPG Projects and Cores, and for expenditure reconciliation. Ms. Bartkus will also help with arranging the monthly meetings of PPG Project Leaders, investigators and Core Leaders, organize seminars, meetings with advisors and handle PPG related travel. She will ensure that all human subject and animal use documentation is current. The Biostatistics portion of Core A will provide statistical expertise for all projects and investigators to ensure rigor and reproducibility for all PPG projects. Drs. Ye and Du will continue to work closely with project leaders and will be available to all PPG investigators to provide state-of-the-art statistical support. To ensure statistical reproducibility, for each PPG-associated analysis performed, a statistical report in HTML or PDF format will be generated, which will document the R programming codes and any simulation seeds used in the analysis. Additionally, all model development procedures will be internally validated using cross-validation or bootstrap methods. The Biostatistics Core supports all 4 Projects. Bioinformatics support will be provided in Core D: The Non-Coding RNA and Bioinformatics Core.

行政和生物统计核心（核心 A）的目的是协调行政和财政 PPG 的活动，为所有项目提供生物统计支持，并确保严格的实验 Linton 博士将负责所有项目的设计和数据分析，并监督 Core A 的所有职能。 拨款经理尼古拉斯·詹金斯 (Nicholas Jenkins) 将与林顿博士密切合作，提供财政监督和管理 PPG 项目和核心的预算方面，包括遵守机构政策和 詹金斯先生将协助制定与赠款相关的预算。 劳伦斯女士将监督财务方面的提交，包括竞争性和非竞争性续展。 她将监督并协调与拨款经理的沟通。 行政官员 Maria Peng 将编制每月预算报表。 她将负责研究人员的项目和核心。 劳伦斯女士和行政助理巴特库斯女士将负责服务核心和项目的财务。 共同负责为所有 PPG 项目生成设备和试剂的采购订单，以及 Bartkus 女士还将帮助安排 PPG 的每月会议。 项目负责人、研究者和核心负责人组织研讨会、与顾问的会议并处理 PPG 她将确保所有人类受试者和动物使用文件都是最新的。 核心 A 将为所有项目和调查人员部分提供统计专业知识，以确保严谨性和 Ye 和 Du 博士将继续与项目负责人密切合作。 向所有 PPG 研究人员提供最先进的统计支持，以确保统计结果。 再现性，对于执行的每个 PPG 相关分析，将提供 HTML 或 PDF 格式的统计报告 生成的，它将记录 R 编程代码和分析中使用的任何模拟种子。 此外，所有模型开发程序都将使用交叉验证或引导程序进行内部验证 生物统计学核心支持所有 4 个项目，生物信息学支持将在核心 D 中提供。 非编码 RNA 和生物信息学核心。