Administrative Core

行政核心

• 批准号: 10271865
• 负责人: Binhua P Zhou
• 金额: $ 65.57万
• 依托单位: UNIVERSITY OF KENTUCKY
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-03-01 至 2026-12-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10271865
• 关键词: Accountability; Address; Administrator; Advanced Malignant Neoplasm; Advisory Committees; Area; Biochemistry; Bioinformatics; Biomedical Research; Biometry; Cancer Center; Cardiovascular Diseases; Centers of Research Excellence; Clinical; Clinical Sciences; Communication; Communication Programs; Coupled; Data; Data Science; Development; Effectiveness; Ensure; Evaluation; Faculty; Fostering; Goals; Health; Incidence; Informatics; Infrastructure; Institutes; Kentucky; Knowledge; Leadership; Malignant Neoplasms; Mediator of activation protein; Mentors; Mentorship; Metabolic; Metabolism; Molecular Medicine; Monitor; National Cancer Institute; Obesity; Oncogenic; Pharmacologic Substance; Pilot Projects; Play; Process; Productivity; Program Evaluation; Research; Research Infrastructure; Research Personnel; Research Training; Resource Sharing; Resources; Role; Scientist; Seasons; Senior Scientist; Services; Structure; System; Translational Research; Universities; Vision; anticancer research; base; biomedical informatics; cancer therapy; career development; clinical center; flexibility; imaging capabilities; improved; innovation; meetings; metabolomics; mortality; multidisciplinary; next generation; novel; programs; skills; success; synergism; therapeutic target; tool; tumor metabolism

PROJECT SUMMARY The University of Kentucky (UK) Center for Cancer and Metabolism (CCM) is a unique multidisciplinary Center of Biomedical Research Excellence (COBRE) embedding a strategically developed, sustainable center infrastructure that cultivates cutting-edge research focused on the role of metabolic dysregulation in cancer development and progression. The Administrative Core provides critical scientific and administrative leadership to advance the goals of the CCM: to develop and sustain a thematically focused multidisciplinary center infrastructure dedicated to defining the role of altered metabolism in the development and treatment of cancer and to use this innovative center structure to develop promising early-stage investigators with enhanced cancer research skills. The goal of the Administrative Core is to increase the scientific productivity of the center’s faculty by delivering efficient administrative services across scientific projects and cores as well as pilot projects through an organizational / leadership framework that supports flexible team-based mentoring and provides for clear accountability. The Administrative Core is the central coordinating hub responsible for integrating highly complementary disciplinary strengths at UK in cancer, metabolism and informatics and leveraging sophisticated metabolomics tools and advanced cancer imaging capabilities in support of data-intensive research focused on cancer metabolism. The core has primary responsibility for facilitating the CCM’s scientific vision, operating on principles grounded in transformational leadership and shared administrative oversight. Administrative Core functions are operationalized through the following 3 specific aims: 1) to provide overall operational management of the center; 2) to facilitate research training, mentoring and career development activities to develop early- stage investigators in cancer and metabolism and expand research in this area through pilot projects; and 3) to conduct overall planning and evaluation of CCM activities and resources. The core implements all administrative activities of the CCM: oversees daily center activities; manages program communications, fiscal processes, meeting organization and advisory committee input; facilitates and expedites interactions among projects and cores; manages the pilot project program; and leads program and project evaluation efforts. The core oversees a total of 4 projects, 2 scientific cores, a biostatistics and bioinformatics support component that is integrated into each project and 4 pilot projects each year. In addition, the core ensures highly effective, well-planned team- based mentorship, including basic and clinical perspectives and external expertise, for early-stage investigators. The core supports CCM investigators through their career development milestones including tenure and promotion stages. In implementing these activities effectively, the Administrative Core contributes substantially to development of a sustainable biomedical research infrastructure dedicated to advancing a cancer metabolism multidisciplinary theme.

项目概要 肯塔基大学（英国）癌症与代谢中心 (CCM) 是一个独特的多学科中心 生物医学卓越研究中心 (COBRE) 嵌入一个战略性发展的可持续中心 培养尖端研究的基础设施，重点关注代谢失调在癌症中的作用 行政核心提供关键的科学和行政领导。 推进 CCM 的目标：发展和维持一个以主题为重点的多学科中心 致力于定义代谢在癌症发展和治疗中的作用的基础设施 并利用这个创新的中心结构来培养具有增强癌症能力的有前途的早期研究人员 行政核心的目标是提高中心教员的科学生产力。 通过跨科学项目和核心以及试点项目提供高效的行政服务 一个组织/领导框架，支持灵活的基于团队的指导，并提供明确的指导 行政核心是负责高度整合的中央协调中心。 英国在癌症、代谢和信息学方面的互补学科优势，并利用先进的 代谢组学工具和先进的癌症成像功能支持数据密集型研究，重点关注 该核心主要负责促进 CCM 的科学愿景，并在其基础上运作。 以变​​革型领导和共同行政监督为基础的原则。 职能通过以下 3 个具体目标来运作： 1) 提供全面的运营管理 2) 促进研究培训、指导和职业发展活动，以培养早期- 癌症和代谢领域的研究人员，并通过试点项目扩大该领域的研究；3) 对CCM活动和资源进行总体规划和评估 核心实施所有行政管理。 CCM 的活动：监督中心的日常活动；管理项目沟通、财务流程、 会议组织和咨询委员会的意见促进和加快项目之间的互动； 核心；管理试点项目计划；并领导计划和项目评估工作。 总共 4 个项目、2 个科学核心、一个集成的生物统计学和生物信息学支持部分 每年都有 4 个试点项目。此外，核心确保高效、精心策划的团队。 为早期研究人员提供基础指导，包括基本和临床观点以及外部专业知识。 该核心支持 CCM 研究人员完成其职业发展里程碑，包括终身教职和晋升 在实施这些活动的过程中，行政核心做出了巨大贡献。 开发可持续的生物医学研究基础设施，致力于促进癌症代谢 多学科主题。